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Volume 17, Number 3—March 2011


Reduction of Coxiella burnetii Prevalence by Vaccination of Goats and Sheep, the Netherlands

Lenny HogerwerfComments to Author , René van den Brom, Hendrik I.J. Roest, Annemarie Bouma, Piet Vellema, Maarten Pieterse, Daan Dercksen, and Mirjam Nielen
Author affiliations: Author affiliations: Utrecht University, Utrecht, the Netherlands (L. Hogerwerf, A. Bouma, M. Pieterse, M. Nielen); Animal Health Service, Deventer, the Netherlands (R. van den Brom, P. Vellema, D. Dercksen); Central Veterinary Institute of Wageningen UR, Lelystad, the Netherlands (H.I.J. Roest)

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Table 6

Univariate survival analysis of PCR Ct values for Coxiella burnetii in positive and doubtful samples from culled animals in 13 small ruminant herds, the Netherlands, January–April 2010*

Uterine fluid
Vaginal mucus
HR (95% CI)
p value
HR (95% CI)
p value
HR (95% CI)
p value
Unvaccinated 1 NA 1 NA 1 NA
Vaccinated 0.49 (0.39–0.70) <0.05 0.34 (0.28–0.42) <0.05 0.54 (0.39–0.75) <0.05

*Ct, cycle threshold; HR, hazard ratio; CI, confidence interval; NA, not applicable.

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