Dengue Virus Serotype 4, Roraima State, Brazil
Figure. A) Boa Vista, Roraima State, Brazil, showing the districts where dengue virus type 4 (DENV-4) was isolated. 1, Liberdade; 2, Buritis; 3, Cauamé; 4, Santa Tereza; 5, Cidade Satélite; 6, Dr. Silvio Leite; 7, Joquel Clube; 8, Sen. Hélio Campos. B) Phylogenetic analysis of the DENV-4 envelope gene sequences (in boldface) constructed by using the neighbor-joining method, showing the cluster formed by Boa Vista and Venenzuela DENV-4 genotype I strains. Bootstrap values were set for 1,000 replicates and are placed over each main node of the tree. ROR1982 represents the DENV-4 isolated in Roraima State during the 1982 epidemic. A to B1–B4 represent genotype I subclades. Thailand 1978 and Thailand 1985 strains represent the Asian genotype II. Scale bar corresponds to 1% nucleotide sequence divergence.