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Volume 17, Number 5—May 2011

Dispatch

Genetic Characterization of West Nile Virus Lineage 2, Greece, 2010

Anna Papa, Tamás Bakonyi, Kyriaki Xanthopoulou, Ana Vázquez, Antonio Tenorio, and Norbert NowotnyComments to Author 
Author affiliations: Author affiliations: Aristotle University, Thessaloniki, Greece (A. Papa, K. Xanthopoulou); Faculty of Veterinary Science, Budapest, Hungary (T. Bakonyi); University of Veterinary Medicine, Vienna, Austria (T. Bakonyi, N. Nowotny); Instituto de Salud Carlos III, Majadahonda, Spain (A. Vázquez, A. Tenorio)

Main Article

Table

Unique amino acid substitutions in the putative nonstructural proteins of the Nea Santa-Greece-2010 lineage 2 West Nile virus*

Strain Protein, aa position
NS1
NS2B
NS3
NS4B
NS5
44 88 119 11 249 14 23 32 49 113 190
Gr-10 (lin. 2) Arg Ile Ile Arg Pro Gly Thr Asn Ala Met Arg
Hu-04 (lin. 2) Arg Ile Val Arg His Ser Thr Asn Thr Val Lys
Other lin. 2 WNV strains Lys Met Val Lys His Ser† Ala Ser Thr‡ Val Lys
NY-99 (lin. 1) Lys Met Val Lys Pro Ser Val Glu Thr Val Lys
Rab-97 (lin. 3) Arg Ile Val Lys Asn Ser Thr Asp Ser Val Lys
Rus-98 (lin. 4) Lys Met Val Arg Thr Gly Ser Ser Ser Val Lys
Ind-80 (lin. 5) Lys Met Val Lys Thr Gly Ala Glu Thr Val Lys

*NS, nonstructural protein; aa, amino acid; lin., lineage; Arg, arginine; Ile, isoleucine; Pro, proline; Gly, glycine; Thr, threonine; Asn, asparagine; Ala, alanine; Met, methionine; Val, valine; His, histidine; Lys, lysine; Ser, serine; WNV, West Nile virus. Abbreviations of strains are explained in the Figure legend. Boldface indicates the His→Pro substitution at aa position 249.
†Except SE-90, WNFCG, Mad-78, and Sarafend (Gly).
‡Except Mad-78 (Ala).

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