Worldwide Distribution of Major Clones of Listeria monocytogenes
Viviane Chenal-Francisque1, Jodie Lopez1, Thomas Cantinelli, Valerie Caro, Coralie Tran, Alexandre Leclercq, Marc Lecuit2, and Sylvain Brisse2
Author affiliations: Author affiliations: Institut Pasteur, Paris, France (V. Chenal-Francisque, J. Lopez, T. Cantinelli, V. Caro, C. Tran, A. Leclercq, M. Lecuit, S. Brisse); World Health Organization Collaborating Center for Listeria, Paris (V. Chenal-Francisque, A. Leclercq, M. Lecuit); Inserm Avenir U604, Paris (M. Lecuit); Université Paris Descartes, Paris (M. Lecuit)
Figure A1. Genetic relationships among 660 Listeria monocytogenes isolates. The graph is a minimum spanning tree based on allelic profiles by using BioNumerics version 6.1 (Applied-Maths, Sint-Martens-Latem, Belgium). The 300 isolates of this study are in blue; the 360 L. monocytogenes isolates and reference strains of our earlier study (12) are in white and gray, respectively. Each circle represents a multilocus sequence typing genotype (ST), the size of which is related to the number of isolates (see legend). Clones, defined as clonal complexes [CC], are composed of groups of STs linked with a single gene difference, denoted as bold lines (see legend); clone number is indicated for the major clones. Links with >2 mismatches are unreliable because many alternatives may exist; links with 7 mismatches are not shown.
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