Antigenic Diversity of Enteroviruses Associated with Nonpolio Acute Flaccid Paralysis, India, 2007–2009
C. Durga Rao , Prasanna Yergolkar1, and K. Subbanna Shankarappa12
Author affiliations: Author affiliations: Indian Institute of Science, Bangalore, India (C.D. Rao, K.S. Shankarappa); National Institute of Virology–World Health Organization–South East Asia Region Polio Laboratory Network, Victoria Hospital, Bangalore (P. Yergolkar); National Institute of Virology, Bangalore (P. Yergolkar); Victoria Hospital, Bangalore (P. Yergolkar)
Figure 4. . . . Phylogenetic tree of viral protein 1 sequences of coxsackievirus B1–B6 isolates generated in comparison with those of strains belonging to different genotypes of B1, B2, B3, B4, B5, and B6 serotypes, India, 2007–2009. Multiple sequence alignments were performed by using ClustalW program (www.genome.jp/tools/clustalw/) and phylogenetic analysis by MEGA5 program (13) with pairwise comparison and maximum composite likelihood nucleotide substitution model. Phylogenetic trees were constructed by UPGMA (unweighted pair group method using arithmetic averages) with statistical significance of the phylogenetic analyses estimated by bootstrap analysis with 1,000 pseudoreplicate datasets.
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