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Volume 18, Number 11—November 2012

Research

Lack of Cross-protection against Bordetella holmesii after Pertussis Vaccination

Xuqing Zhang, Laura S. Weyrich, Jennie S. Lavine, Alexia T. Karanikas, and Eric T. HarvillComments to Author 
Author affiliations: The Pennsylvania State University, University Park, Pennsylvania, USA

Main Article

Figure 6

Supplementation of whole-cell pertussis vaccine (wP) with B. holmesii- but not B. pertussis- specific antibodies. Groups of four wP-vaccinated C57BL/6 mice were left untreated (none) or treated with naive serum, wP-induced sereum, or whole-cell Bordetella holmesii vaccine (wH)–induced serum, and challenged with B. holmesii. Bacterial numbers in the lungs on day 3 postinoculation are shown. Error bars indicate SE. *p<0.05.

Figure 6. . . . Supplementation of whole-cell pertussis vaccine (wP) with B. holmesii- but not B. pertussis- specific antibodies. Groups of four wP-vaccinated C57BL/6 mice were left untreated (none) or treated with naive serum, wP-induced sereum, or whole-cell Bordetella holmesii vaccine (wH)–induced serum, and challenged with B. holmesii. Bacterial numbers in the lungs on day 3 postinoculation are shown. Error bars indicate SE. *p<0.05.

Main Article

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