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Volume 18, Number 11—November 2012

Dispatch

Susceptibility of Children to Sapovirus Infections, Nicaragua, 2005–2006

Filemón Bucardo1, Beatrice Carlsson1, Johan Nordgren, Göran Larson, Patricia Blandon, Samuel Vilchez, and Lennart SvenssonComments to Author 
Author affiliations: University of León, León, Nicaragua (F. Bucardo, P. Blandon, S. Vilchez); Linköping University, Linköping, Sweden (F. Bucardo, B. Carlsson, J. Nordgren, L. Svensson); and University of Gothenburg, Göteborg, Sweden (G. Larson)

Main Article

Table 2

Distribution of ABO blood groups, Lewis antigens, and FUT2 428 genotypes among SaV- infected children and healthy controls, León, Nicaragua, 2005–2006*

Variable No. (%) SaV infected No. (%) controls† OR (95% CI) p value‡
Blood group

O

16 (73) 87 (66) 1.3 (0.49–3.7) 0.63

A

2 (9) 26 (20) 0.4 (0.09–1.8) 0.37

B

3 (13.5) 13 (10) 1.4 (0.37–5.5) 0.82

AB

1 (4.5) 5 (4) 1.2 (0.13–11) 1.00
Lewis phenotype

Lea-b+

17 (77.5) 93 (71) 1.3 (0.46–3.91) 1.00

Lea+b-

2 (9) 5 (4) 2.5 (0.45–13.7) 0.26

Lea-b-

3 (13.5) 32 (25) 0.48 (0.13−1.7) 0.41
FUT2 SNP (428G→A)

SeSe

13 (59) 69 (53) 1.3 (0.52–3.2) 0.64

Sese428

7 (32) 58 (44) 0.59 (0.22–1.5) 0.35

se428se428

2 (9) 4 (3) 3.2 (0.55–18.00) 0.2
Secretor status

Secretor

20 (91) 123 (94) 0.65 (0.13–3.3) 0.63

Nonsecretor

2 (9) 8 (6) 1.5 (0.3–7.8) 0.63

*SaV, sapovirus; OR, odds ratio; FUT2, fucosyltransferase gene 2; SNP, single nucleotide polymorphism; SeSe, homozygous wild type at FUT2 428; Sese428, heterozygous carrier of FUT2 428 non-sense mutation; se428se428, homozygous carrier of the non-sense mutation at nt 428 in the FUT2 gene
†From Bucardo et al. (14).
‡Fischer exact test.

Main Article

1These authors contributed equally to this article.

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