Volume 18, Number 3—March 2012
Research
A Systematic Approach for Discovering Novel, Clinically Relevant Bacteria
Table 3
Anatomical sites and possible novel bacterial isolates*
| Source | Identity, % | Best species-level match | Cluster | Gram stain morphology | Comment† |
|---|---|---|---|---|---|
| Tissue | 98.8 | Acidovorax delafieldii | N | GNR | |
| Tissue | 97.2 | Actinoallomurus fulvus | N | GPR | |
| CSF | 98.3 | Actinomyces meyeri | Y | GPR | |
| Pericardial fluid | 94.4 | Anaerococcus prevotii | N | GPC | |
| Tissue | 94.8 | Capnocytophaga sputigena | N | GNR | |
| CSF | 93.8 | Chryseobacterium taiwanense | Y | GNR | Planobacterium taklimakanense, short reference sequence |
| CSF | 98.3 | Corynebacterium mucifaciens | Y | GPR | |
| Tissue | 98.6 | Cupriavidus gilardii | Y | GNR | |
| CSF | 97.1 | Erwinia chrysanthemi | Y‡ | GNR | |
| Tissue | 97.7 | E. chrysanthemi | Y‡ | GNR | |
| CSF | 97.2 | Globicatella sanguinis | Y | GPC | |
| Tissue | 96.2 | Kocuria kristinae | Y | GPC | |
| CSF | 92.4 | Desmospora activa | Y | GPR | Kroppenstedtia eburnea |
| Synovial fluid | 91.2 | Laceyella sacchari | N | GVR | |
| Tissue | 96.0 | Microbacterium thalassium | Y‡ | GPR | |
| Tissue | 95.9 | M. thalassium | Y‡ | GVR | |
| Tissue | 96.9 | Neisseria canis | N | GNC | |
| Tissue | 97.9 | Neisseria zoodegmatis | Y | GNCB | |
| Biopsy specimen | 98.7 | Nocardia beijingensis | Y | GPR | |
| Brain | 98.9 | Nocardia nova | Y | GPR | |
| Tissue | 98.9 | Nocardia transvalensis | N | GPR | |
| CSF | 96.1 | Phenylobacterium immobile | N | GNR | |
| Tissue | 97.5 | Prosthecomicrobium enhydrum | N | GVR | |
| Tissue | 95.2 | Pseudomonas pohangensis | Y‡ | GNR | |
| Tissue | 95.2 | Pseudomonas pohangensis | Y‡ | GNR | |
| CSF | 98.5 | Rothia dentocariosa | Y | GPR | Rothia aeria, short reference sequence |
| Tissue | 98.0 | Streptococcus mitis | Y | GPC | |
| Valve | 96.8 | Streptococcus oralis | Y | GPC | |
| CSF | 98.0 | Streptococcus sanguinis | Y | GPC | |
| CSF | 96.4 | Streptomyces prasinopilosus | N | GPR | |
| CSF | 96.8 | Terrabacter terrae | N | GPC | |
| Tissue | 97.8 | Williamsia serinedens | N | GPR | Williamsia deligens, short reference sequence |
*GNR, gram-negative rods; GPR, gram-positive rods; CSF, cerebrospinal fluid; GPC, gram-positive cocci; GVR, gram-variable rods; GNC, gram-negative cocci; GNCB, gram-negative coccobacilli; Y, isolates belonging to tentative novel taxa represented multiple times in this study.
†Results of manual review of BLASTn analysis (23).
‡These pairs of isolates belong to the same 3 respective clusters.
1These authors contributed equally to this article.
