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Volume 18, Number 4—April 2012

Research

Identification of Risk Factors for Chronic Q Fever, the Netherlands

Linda M. KampschreurComments to Author , Sandra Dekker, Julia C.J.P. Hagenaars, Peter J. Lestrade, Nicole H.M. Renders, Monique G.L. de Jager-Leclercq, Mirjam H.A. Hermans, Cornelis A.R. Groot, Rolf H.H. Groenwold, Andy I.M. Hoepelman, Peter C. Wever, and Jan Jelrik Oosterheert
Author affiliations: University Medical Centre Utrecht, Utrecht, the Netherlands (L.M. Kampschreur, R.H.H. Groenwold, A.I.M Hoepelman, J.J. Oosterheert); VU University, Amsterdam, the Netherlands (S. Dekker); Jeroen Bosch Hospital, ’s-Hertogenbosch, the Netherlands (J.C.J.P. Hagenaars, P.J. Lestrade, N.H.M. Renders, M.H.A. Hermans, P.C. Wever); Bernhoven Hospital, Oss/Veghel, the Netherlands (M.G.L. de Jager-Leclercq, C.A.R. Groot)

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Figure 2

Goodness-of-fit models for case–control study to identify risk factors for chronic Q fever, the Netherlands. A) All chronic Q fever cases (n = 105); area under the curve (c-statistic) 0.77 (95% CI 0.71–0.83); p <0.001. B) Proven and probable chronic Q fever cases (n = 72); c-statistic 0.86 (95% CI 0.81–0.92); p <0.001. C) Proven chronic Q fever cases (n = 44); c-statistic 0.91 (95% CI 0.85–0.97); p <0.001. Patient risk factors included in the model (no. observations): A) valvular surger

Figure 2. Goodness-of-fit models for case–control study to identify risk factors for chronic Q fever, the Netherlands. A) All chronic Q fever cases (n = 105); area under the curve (c-statistic) 0.77 (95% CI 0.71–0.83); p<0.001. B) Proven and probable chronic Q fever cases (n = 72); c-statistic 0.86 (95% CI 0.81–0.92); p<0.001. C) Proven chronic Q fever cases (n = 44); c-statistic 0.91 (95% CI 0.85–0.97); p<0.001. Patient risk factors included in the model (no. observations): A) valvular surgery (18); vascular prosthesis (15); aneurysm (12); nonhematologic malignancy (16); age, continuous, mean 63.9 y; B) valvular surgery (18); vascular prosthesis (15); aneurysm (12); renal insufficiency (12); age, continuous, mean 67.3 y; C) valvular surgery (10); vascular prosthesis (14); aneurysm (9); renal insufficiency (9); age, continuous, mean 68.4.

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