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Volume 18, Number 9—September 2012

Letter

blaOXA-181–positive Klebsiella pneumoniae, Singapore

Tse H. KohComments to Author , Delphine Y.H. Cao, Kian S. Chan, Limin Wijaya, Stewart B.G. Low, Mun S. Lam, Eng E. Ooi, and Li-Yang Hsu
Author affiliations: National University of Singapore, Singapore (T.H. Koh, L.-Y. Hsu); Singapore General Hospital, Singapore (T.H. Koh, D.Y.H. Cao, K.S. Chan, L. Wijaya); Mount Alvernia Hospital, Singapore (S.B.G. Low); Mount Elizabeth Medical Centre, Singapore (M.S. Lam); and Duke–National University of Singapore–Graduate Medical School, Singapore (E.E. Ooi)

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Table

Antimicrobial drug susceptibilities of 3 blaOXA-181–positive Klebsiella pneumoniae isolates, Singapore*

Drug MIC (mg/L)
DB53879_11 DX1083_11 BL21479_11
Ampicillin ≥256 ≥256 ≥256
Amoxicillin/clavulanate ≥256 ≥256 ≥256
Piperacillin/tazobactam ≥256 ≥256 ≥256
Cefuroxime ≥256 ≥256 ≥256
Ceftriaxone ≥32 ≥32 ≥32
Ceftazidime ≥256 ≥256 ≥256
Cefepime ≥256 ≥256 ≥256
Ertapenem ≥32 ≥32 ≥32
Imipenem 16 ≥32 16
Meropenem ≥32 ≥32 ≥32
Doripenem ≥32 ≥32 ≥32
Ciprofloxacin ≥32 ≥32 ≥32
Levofloxacin ≥32 ≥32 ≥32
Gentamicin ≥256 ≥256 ≥256
Amikacin ≥256 ≥256 ≥256
Sulfamethoxazole/trimethoprim ≥32 ≥32 ≥32
Tetracycine ≥256 ≥256 8
Tigecycline 4 4 4
Polymyxin B 0.5 1 4

*OXA-181, oxacillinase-181.

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