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Volume 19, Number 10—October 2013

Research

Immunogenic Mycobacterium africanum Strains Associated with Ongoing Transmission in The Gambia

Florian GehreComments to Author , Martin Antonio, Jacob K. Otu, Neneh Sallah, Oumie Secka, Tutty Faal, Patrick Owiafe, Jayne S. Sutherland, Ifedayo M. Adetifa, Martin O. Ota, Beate Kampmann, Tumani Corrah, and Bouke C. de Jong
Author affiliations: Medical Research Council Unit, Fajara, The Gambia (F. Gehre, M. Antonio, J.K. Otu, N. Sallah, O. Secka, T. Faal, P. Owiafe, J.S. Sutherland, I.M. Adetifa, M.O. Ota, B. Kampmann, T. Corrah, B.C. de Jong); Institute for Tropical Medicine, Antwerp, Belgium (F. Gehre, B.C. de Jong); Imperial College London, London, UK (B. Kampmann); New York University, New York, New York, USA (B.C. de Jong)

Main Article

Table 2

Emerging Mycobacterium tuberculosis complex strains as detected by DESTUS from samples collected in West Africa*

Study site and years p value†
Guinea Bissau, 1989–2008
SIT 181 (Afri_1) 3.8 × 10–8
SIT 187 (Afri_1)
4.7 × 10–6
The Gambia, 2002–2009
SIT 181 (Afri_1) 2.5 × 10–30
SIT 187 (Afri_1) 5.1 × 10–4
SIT 60 (M. tuberculosis) 1.5 × 10–6
SIT 61 (M. tuberculosis) 2.9× 10–4
SIT 183 (M. tuberculosis) 3.9 × 10–4

*Years shown indicate when samples were collected. DESTUS, Detect Emerging Strains of Tuberculosis by Using Spoligotyping (13); SIT, shared international type; Afri_1, M. africanum West Africa 2.
†After Sidak Dunn correction for type I error.

Main Article

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