Emergence of Vaccine-derived Polioviruses, Democratic Republic of Congo, 2004–2011
Nicksy Gumede , Olivia Lentsoane, Cara C. Burns, Mark Pallansch, Esther de Gourville, Riziki Yogolelo, Jean Jacques Muyembe-Tamfum, Adrian Puren, Barry D. Schoub, and Marietjie Venter
Author affiliations: National Institute for Communicable Diseases, Johannesburg, South Africa (N. Gumede, O. Lentsoane, A. Puren, B.D. Schoub, M. Venter); University of Witwatersrand, Johannesburg (N. Gumede, B.D. Schoub); University of Pretoria, Pretoria, South Africa (M. Venter); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (C.C. Burns, M. Pallansch); World Health Organization, Geneva, Switzerland (E. de Gourville); National Institute for Biomedical Research, Kinshasa/Gombe, Democratic Republic of Congo (R. Yogolelo, J.J. Muyembe-Tamfum)
Figure 3. . Viral protein phylogenetic relationships among vaccine-derived poliviruses isolated from patients with acute flaccid paralysis, Democratic Republic of Congo, 2004–2011. The tree was rooted to the Sabin type 2 poliovirus sequence. The year of onset of paralysis is indicated at the beginning of each virus name, followed by a 5-digit identifier and the province of the case-patient. The numbers of nucleotide differences from the Sabin 2 prototype viral protein 1 sequence are indicated, followed by the name of the lineage. Bootstrap values >80 are indicated on the tree. Scale bar indicates nucleotide substitutions per site.
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