Volume 19, Number 11—November 2013
CME ACTIVITY - Synopsis
Tropheryma whipplei Endocarditis
Florence Fenollar, Marie Célard, Jean-Christophe Lagier, Hubert Lepidi, Pierre-Edouard Fournier, and Didier Raoult
Table 1
Epidemiologic and clinical characteristics of 28 patients with Tropheryma whipplei endocarditis*
| Patient (reference) | Area of origin | Age, y | IS | Cardiac history | Arthralgia duration, y | Weight loss | Cardiac symptoms | Fever | Involved valves | Vegetation |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PACA | 80 | N | PM | Y (15) | N | HF and AIS | N | AV | Y |
| 2 | Corsica† | 58 | N | N | Y (8) | N | HF | Y | AV+MV | N |
| 3 | Rhône-Alpes | 54 | N | N | Y (3) | Y | HF | Y | AV | Y |
| 4 | Rhône-Alpes | 45 | N | BAV | N | N | Stroke | Y | AV | Y |
| 5 | Rhône-Alpes | 56 | N | CS | N | N | HF | Y | AV | Y |
| 6 | PACA | 59 | Y | N | Y (35) | N | HF | N | AV | N |
| 7 | Pays de la Loire | 50 | N | N | Y (NA) | N | HF | N | AV+MV | Y |
| 8 | Picardie | 51 | N | N | N | N | Stroke | N | AV | Y |
| 9 | PACA | 79 | N | AVB | Y | N | HF | N | AV | Y |
| 10 | Lorraine | 50 | N | N | N | N | HF | N | MV | N |
| 11 | Rhône-Alpes | 62 | N | N | Y | N | HF | N | AV | Y |
| 12 | PACA | 58 | N | BAV | Y | Y | HF | Y | AV | Y |
| 13 (2) | Rhône-Alpes | 71 | N | N | N | N | HF | N | AV | Y |
| 14 (18) | Rhône-Alpes | 57 | Y | N | Y (4) | N | HF+PAE | Y | AV | N |
| 15 (2) | Poitou-Charentes | 68 | N | N | N | N | HF | Y | AV | Y |
| 16 (2) | Pays de la Loire | 48 | N | AVI | Y (NA) | N | HF | Y | AV | Y |
| 17 (19) | Languedoc-Roussillon | 70 | Y | N | Y (27) | N | HF | Y | AV | Y |
| 18 (2) | Pays de la Loire | 71 | N | MVI | Y (NA) | N | HF | Y | MV | Y |
| 19 (2) | Pays de la Loire | 57 | Y | N | Y (10) | Y | HF | Y | AV+MV | N |
| 20 (2) | Rhône-Alpes | 67 | N | N | Y (4) | N | Stroke | N | AV | N |
| 21 (2) | Rhône-Alpes | 51 | Y | N | Y (6) | N | PAE | N | AV+TV | Y |
| 22 (2) | Pays de la Loire | 58 | N | AAR | Y (NA) | N | PAE | N | AV | Y |
| 23 (2) | Rhône-Alpes | 60 | Y | N | Y (2) | N | HF | N | AV+MV | Y |
| 24 (2) | Rhône-Alpes | 61 | N | AAR | Y (4) | N | Stroke | N | AV+MV | Y |
| 25 (2) | Rhône-Alpes | 63 | N | N | Y (3) | N | PAE+stroke | N | AV | Y |
| 26 (5) | Canada | 42 | N | AAR | N | Y | HF | N | AV+MV | Y |
| 27 (2) | Rhône-Alpes | 40 | Y | AAR | Y (5) | N | HF | N | AV | Y |
| 28 (2) | Rhône-Alpes | 55 | N | N | Y (5) | Y | Stroke | N | MV | Y |
*All patients were male, and none had diarrhea. IS, immunosuppressive therapy; PACA, Provence-Alpes-Côte-d’Azur; N, no; PM, pacemaker; Y, yes; HF; heart failure; AIS, acute ischemic stroke; AV, aortic valve; MV, mitral valve; BAV, bicuspid aortic valve; CS, coronary stent; AVB, aortic valve bioprosthesis; AVI, aortic valve insufficiency; MVI, mitral valve insufficiency; NA, not available; PAE, peripheral arterial embolism; AAR, acute articular rheumatism.
†This patient was from Poland but resided in Corsica for 8 years.
Page created: October 28, 2013
Page updated: October 28, 2013
Page reviewed: October 28, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.