Emerging Infectious Disease ISSN: 1080-6059

Hepatitis E Virus Mixed Infection in Immunocompetent Patient

Donald B. Smith

, Jeff Vanek, Louise Wellington, Ingolfur Johannessen, Sandeep Ramalingam, and Peter Simmonds

Author affiliations: Author affiliations: University of Edinburgh, Edinburgh, Scotland, United Kingdom (D.B.S., P.S.); Royal Infirmary of Edinburgh, Edinburgh (J.V., I.J., S.R.); NHS Lothian, Edinburgh (L.W.)

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Figure

Phylogenetic tree of hepatitis E virus hypervariable region variants. A neighbor-joining tree of hypervariable region sequences was constructed by using MEGA 4 (15). A and B indicate sequences for virus populations A and B. Sequences from the patient studied here (patient 21) belonging to virus population A are indicated by a solid square, and those belonging to virus population B are indicated by a solid circle. Other sequences obtained in the same laboratory are indicated by an open circle. Cl

Figure. . . Phylogenetic tree of hepatitis E virus hypervariable region variants. A neighbor-joining tree of hypervariable region sequences was constructed by using MEGA 4 (15). A and B indicate sequences for virus populations A and B. Sequences from the patient studied here (patient 21) belonging to virus population A are indicated by a solid square, and those belonging to virus population B are indicated by a solid circle. Other sequences obtained in the same laboratory are indicated by an open circle. Closely related genotype 3 sequences obtained from GenBank are identified by their accession number. Bootstrap support (1,000 replicates) for branches of >70% are indicated. Scale bar indicates nucleotide substitutions per site.

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