Novel Respiratory Syncytial Virus Subtype ON1 among Children, Cape Town, South Africa, 2012
Ziyaad Valley-Omar , Rudzani Muloiwa, Nai-Chung Hu, Brian Eley, and Nei-Yuan Hsiao
Author affiliations: Author affiliations: University of Cape Town, Cape Town, South Africa (Z. Valley-Omar, R. Muloiwa, B. Eley, N.-Y. Hsiao); National Institute for Communicable Diseases, Cape Town (Z. Valley-Omar, N.-C. Hu, N.-Y. Hsiao); Red Cross War Memorial Children’s Hospital, Cape Town (R. Muloiwa, B. Eley); National Health Laboratory, Cape Town (N.-Y. Hsiao)
Figure. . . Alignment of deduced amino acid sequences for ON1 isolates from South Africa (Patient 1–8, accession nos. JX885730–JX885737) and Canada (ON67 and ON138) with NA1 isolates (Patient 9–12) from South Africa. A) Variable domain sequence copied, B) Duplicated sequence inserted into variable domain, C) Characteristic amino acid substitutions that distinguish ON1 from NA1. D) Amino acid substitution (E308K) (position 284 before insertion) that distinguishes between most ON1 isolates from South Africa (Patient 2–8) from those from Canada (ON67 and ON138) ON1.
The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.