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Volume 19, Number 4—April 2013

CME ACTIVITY

Serotype IV and Invasive Group B Streptococcus Disease in Neonates, Minnesota, USA, 2000–20101

Earning CME Credit

To obtain credit, you should first read the journal article. After reading the article, you should be able to answer the following, related, multiple-choice questions. To complete the questions (with a minimum 70% passing score) and earn continuing medical education (CME) credit, please go to www.medscape.org/journal/eid. Credit cannot be obtained for tests completed on paper, although you may use the worksheet below to keep a record of your answers. You must be a registered user on Medscape.org. If you are not registered on Medscape.org, please click on the New Users: Free Registration link on the left hand side of the website to register. Only one answer is correct for each question. Once you successfully answer all post-test questions you will be able to view and/or print your certificate. For questions regarding the content of this activity, contact the accredited provider, CME@medscape.net. For technical assistance, contact CME@webmd.net. American Medical Association’s Physician’s Recognition Award (AMA PRA) credits are accepted in the US as evidence of participation in CME activities. For further information on this award, please refer to http://www.ama-assn.org/ama/pub/category/2922.html. The AMA has determined that physicians not licensed in the US who participate in this CME activity are eligible for AMA PRA Category 1 Credits™. Through agreements that the AMA has made with agencies in some countries, AMA PRA credit may be acceptable as evidence of participation in CME activities. If you are not licensed in the US, please complete the questions online, print the certificate and present it to your national medical association for review.

Article Title:
Serotype IV and Invasive Group B Streptococcus Disease in Neonates, Minnesota, USA, 2000–2010

CME Questions

1. You are seeing a 2-day-old male infant with fever to 38.3°C and some irritability with poor feeding. You suspect that this child might have group B Streptococcus (GBS) infection. Which of the following statements regarding GBS infection among infants is most accurate?

A. Early-onset (EO) GBS infection is defined by infection between birth and day 6 of life

B. Late-onset (LO) GBS infection is defined by infection between 1 to 3 months of life

C. Screening for GBS in the third trimester has had no effect on the prevalence of EO disease among infants

D. Screening for GBS in the third trimester has primarily reduced the prevalence of LO disease among infants

2. What should you consider regarding the epidemiology of GBS disease in the current study?

A. There were more LO vs EO cases of GBS disease

B. Early-onset GBS was almost always associated with cerebrospinal fluid infection

C. Most infants with EO disease were full-term

D. There were no cases of GBS disease after infants were at least 3 months old

3. What were the most common serotypes of GBS among infected children in the current study?

A. Ib, II

B. III, Ia

C. IV, Ib

D. IV, V

4. What should you consider regarding infection with serotype IV GBS among children in the current study?

A. Type IV was associated with higher rates of LO vs EO disease

B. The mortality rate associated with type IV infection was 50%

C. Type IV disease produced higher degrees of fever compared with other serotypes

D. Type IV disease was associated with higher rates of antimicrobial resistance in 2010 compared with other serotypes

Activity Evaluation

1. The activity supported the learning objectives.

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2. The material was organized clearly for learning to occur.

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3. The content learned from this activity will impact my practice.

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4. The activity was presented objectively and free of commercial bias.

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