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Volume 19, Number 6—June 2013

Research

Characteristics of Group A Streptococcus Strains Circulating during Scarlet Fever Epidemic, Beijing, China, 2011

Peng Yang1, Xiaomin Peng1, Daitao Zhang, Shuangsheng Wu, Yimeng Liu, Shujuan Cui, Guilan Lu, Wei Duan, Weixian Shi, Shuang Liu, Jing Li, and Quanyi WangComments to Author 
Author affiliations: Beijing Center for Disease Prevention and Control, Beijing, China; and Capital Medical University School of Public Health, Beijing

Main Article

Table 2

Results of multivariate analyses for factors associated with 4 clinical signs of scarlet fever in patients with confirmed GAS infection, Beijing, China, 2011*

Factor Clinical sign of scarlet fever†
Strawberry tongue
Red rash
Pastia lines
Circumoral pallor
Yes, n = 293 No, n = 354 OR (95% CI), p value Yes, n = 430 No, n = 217 OR (95% CI), p value Yes, n = 79 No, n = 568 OR (95% CI), p value Yes, n = 63 No, n = 584 OR (95% CI), p value
emm type
12 232 (79.2) 262 (74.0) Ref 331 (77.0) 163 (75.1) Ref 57 (72.2) 437 (76.9) Ref 43 (68.3) 451 (77.2) Ref
1 51 (17.4) 60 (16.9) 1.03 (0.68–1.58), 0.884 83 (19.3) 28 (12.9) 1.63 (1.01–2.62), 0.046 20 (25.3) 91 (16.0) 1.80 (1.02–3.16), 0.043 18 (28.6) 93 (15.9) 2.15 (1.17–3.93), 0.013
Other‡
10 (3.4)
32 (9.0)
0.40 (0.19–0.84), 0.016

16 (3.7)
26 (12.0)
0.35 (0.18–0.68), 0.002

2 (2.5)
40 (7.0)
0.40 (0.09–1.72), 0.218

2 (3.2)
40 (6.8)
0.54 (0.12–2.31), 0.402
Age <5 y
138 (47.1)
108 (30.5)
2.04 (1.46–2.83), <0.001

193 (44.9)
53 (24.4)
2.52 (1.74–3.65), <0.001

35 (44.3)
211 (37.1)
1.40 (0.86–2.27), 0.182

27 (42.9)
219 (37.5)
1.29 (0.75–2.22), 0.356
Female sex
105 (35.8)
140 (39.5)
1.09 (0.78–1.51), 0.630

157 (36.5)
88 (40.6)
1.09 (0.77–1.55), 0.615

36 (45.6)
209 (36.8)
0.65 (0.40–1.05), 0.079

28 (44.4)
217 (37.2)
0.69 (0.40–1.18), 0.171
Interval >2 d§ 51 (17.4) 39 (11.0) 1.87 (1.18–2.97), 0.008 61 (14.2) 29 (13.4) 1.19 (0.73–1.95), 0.489 7 (8.9) 83 (14.6) 0.58 (0.26–1.31), 0.190 3 (4.8) 87 (14.9) 0.29 (0.09–0.94), 0.040

*Four multivariate unconditional logistic regression analyses were separately conducted to examine factors for each clinical sign of scarlet fever. Scarlet fever and pharyngitis patients from whom GAS was isolated were identified as confirmed GAS patients. Boldface font indicates statistical significance. GAS, group A Streptococcus; OR, odds ratio; Ref, reference.
†Data are number (%) patients unless otherwise indicated.
‡Other emm types included types 4, 11, 22, 75, and 89.
§Interval between illness onset and hospital visit.

Main Article

1These authors contributed equally to this article.

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