Volume 23, Number 2—February 2017
Dispatch
Increasing Antibiotic Resistance in Shigella spp. from Infected New York City Residents, New York, USA
Kenya Murray, Vasudha Reddy, John Kornblum, HaeNa Waechter, Ludwin F. Chicaiza, Inessa Rubinstein, Sharon Balter, Sharon K. Greene, Sarah L. Braunstein, Jennifer L. Rakeman, and Catherine M. Dentinger
Table 2
Characteristics associated with azithromycin or ciprofloxacin resistance among case-patients with Shigella flexneri and S. sonnei infections, New York City, New York, USA, March 22, 2013–May 31, 2015*
| Characteristic | No. (%) case-patients |
Crude OR (95% CI)§ | Adjusted OR (95% CI)§ | |
|---|---|---|---|---|
| Resistant, n = 152† | Susceptible, n = 521‡ | |||
| Male sex |
140 (92.1) |
304 (58.4) |
8.33 (4.50–15.40) |
3.27 (1.63–6.55) |
| Age, y | ||||
| 0–17 | 8 (5.3) | 251 (48.2) | Referent | Referent |
| 18–64 | 136 (89.5) | 256 (49.1) | 16.67 (8.00–34.73) | 7.77 (3.52–17.14) |
| >65 |
8 (5.3) |
14 (2.7) |
17.93 (5.86–54.84) |
11.94 (3.63–39.33) |
| Neighborhood poverty, %¶ | ||||
| <10 | 30 (19.7) | 85 (16.9) | Referent | Referent |
| 10–<20 | 58 (38.2) | 135 (26.9) | 1.22 (0.73–2.04) | 1.29 (0.73–2.29) |
| 20–<30 | 41 (27.0) | 108 (21.5) | 1.08 (0.62–1.86) | 1.32 (0.71–2.47) |
| 30–100 |
23 (15.1) |
174 (34.7) |
0.38 (0.21–0.68) |
0.57 (0.29–1.10) |
| Species | ||||
| S. flexneri |
90 (59.2) |
140 (26.7) |
3.95 (2.71–5.76) |
1.91 (1.25–2.92) |
| HIV-diagnosed | ||||
| Yes | 82 (54.0) | 99 (19.0) | 4.99 (3.39–7.35) | 1.44 (0.91–2.30) |
*N = 683 sporadic cases. OR, odds ratio.
†S. boydii (n = 1) omitted.
‡S. boydii (n = 6) and S. dysenteriae (n = 3) omitted.
§Values reported in bold are significant, calculated by using bivariate or multivariable (sex, age, neighborhood poverty, species, and HIV diagnosis) logistic regression.
¶Percentage of residents below federal poverty level, per American Community Survey, 2009–2013; 19 missing.
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Page updated: January 17, 2017
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