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Volume 3, Number 2—June 1997

Synopsis

Borna Disease

Carolyn G. Hatalski, Ann J. Lewis, and W. Ian LipkinComments to Author 
Author affiliations: University of California, Irvine, California, USA

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Table 2

Borna disease virus nucleic acid in patients with various diseases

Prevalence
Disease Tissue Disease (%) Controls (%) Divergence* Ref.
Psychiatric PBMC (4/6) 66.7 (0/10) 0 0-3.6 (22)
(various) PBMC (5/12) 41.7 (0/23) 0 0-4 (27)
PBMC (22/60) 37 (8/172) 4.7 (24, 25)
PBMC-coculture (3/32) 9.4 (0/5) 0 0.07-0.83 (23, 53)
Affective PBMC (1/3) 33.3 (0/23) 0 (27)
PBMC (1/6) 16.7 (0/36) 0 (51)
PBMC (0/9) 0 (56)
Schizophrenia PBMC (7/11) 63.6 (0/23) 0 (27)
PBMC (5/49) 10.2 (0/36) 0 (51)
PBMC 4.2-9.3 (54)
Brain (0/3) 0 (0/3) 0 (55)
CSF (0/48) 0 (0/9) 0 (55)
PBMC (0/9) 0 (0/9) 0 (55)
PBMC (0/26) 0 (56)
CFS PBMC (3/25) 12 6.0-14 (26)
Hippocampal sclerosis Brain (4/5) 80 (53)

Abbreviations: PBMC, peripheral blood mononuclear cells; CSF, cerebrospinal fluid; CFS, chronic fatigue syndrome.
*Divergence of P-gene nucleotide sequence from common BDV isolates (strain V [4] and He/80 [9]).

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