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Volume 4, Number 1—March 1998

Dispatch

Laboratory Survey of Drug-Resistant Streptococcus pneumoniae in New York City, 1993—1995

Richard Heffernan, Kelly Henning, Anne Labowitz, Annette Hjelte, and Marcelle Layton
Author affiliations: New York City Department of Health, New York, New York, USA

Main Article

Table 1

Penicillin resistance among Streptococcus pneumoniae isolates at New York City hospital laboratories

No. of isolates 1993
No. (%) 1994
No. (%) 1995
No. (%)
Screened with oxacillin diska 3,227 4,133 4,912
zone size < 19 mmb 273 (9) 549 (13) 995 (20)
Screened and confirmed with approved MICc 1,229 2,491 3,535
zone size < 19 mm 154 (13) 350 (14) 704 (20)
Id 70 (6) 209 (8) 310 (9)
Rd 19 (2) 115 (5) 222 (6)
Sterile-site isolates screened and confirmed with MICe 462 649 1,321
I 16 (3) 66 (10) 83 (6)
R 5 (1) 20 (3) 65 (5)
Nonsterile isolates screened and confirmed with MICf 456 662 1,596
I 12 (3) 83 (13) 200 (13)
R 5 (1) 31 (5) 110 (7)

aNumber of laboratories reporting oxacillin disk diffusion test results in 1993, 1994, 1995 was 33, 40, 51, respectively.
bOxacillin disk diffusion test zone size.
cApproved penicillin MIC tests include antibiotic gradient strips and broth dilution or micro-dilution using Mueller-Hinton broth supplemented with 2-5% lysed horse blood. Number of laboratories reporting MIC test results in 1993, 1994, 1995 was 10, 22, 35, respectively.
dI=Penicillin-intermediate (MIC > 0.1 and 1.0 µg/ml); R=Penicillin-resistant (MIC > 2.0 µg/ml).
eNumber of laboratories reporting sterile site isolate results in 1993, 1994, 1995 was 8, 12, 32, respectively.
fNumber of laboratories reporting nonsterile site isolate results in 1993, 1994, 1995 was 5, 9, 28, respectively.

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