Figure 3. Cytolysin favors the appearance of circulating enterococci. In this experiment, 107 CFU of E. faecalis, either cytolytic FA2-2(pAM714) (60) or noncytolytic FA2-2(pAM771) (64), were intraperitoneally injected (45) into groups of five BalbC mice. Viable bacteria in liver, spleen, and the bloodstream were enumerated 48 hrs following injection, and significance assessed by Student's t-test. (P. Coburn, L.E. Hancock, and M.S. Gilmore, in preparation).