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Volume 5, Number 1—February 1999

Research

Natural History of Sin Nombre Virus in Western Colorado

Charles H. Calisher*, William Sweeney*, James N. Mills†, and Barry J. Beaty*
Author affiliations: *Colorado State University, Fort Collins, Colorado, USA;; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA

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Table 2

Incidence of immunoglobulin G antibody reactive with Sin Nombre virus in Peromyscus maniculatus (deer mice) recaptured and sampled at least twice at Fort Lewis (June 1994–October 1997) and P. maniculatus and P. truei (pinyon mice) recaptured and sampled at least twice at Molina, western Colorado (October 1994–October 1997)

Species/
location Sex No. at riska No.of new infections Cum. %
antibody-pos. Mouse mos. of observationb Incidencec
Deer mice/ Grid A 38 4 10.5 88 4.6
Ft. Lewis male 17 2 5.9 42 4.8
female 21 2 9.5 46 4.4
Grid B 11 3 27.3 27.5 10.9
male 6 2 33.3 22 9.1
female 5 1 20.0 5.5 18.2
Grids A + B 49 7 14.3 115.5 6.1
male 23 4 17.4 64 6.3
female 26 3 11.5 51.5 5.8
Deer mice/ Grid A 59 5 8.5 179.5 2.8
Molina male 33 3 11.0 94 3.2
female 26 2 7.7 85.5 2.3
Grid B 7 0 0 12.0 0
male 4 0 0 7.5 0
female 3 0 0 4.5 0
Grids A + B 66 5 7.6 191.5 2.6
male 37 3 8.1 101.5 3.0
female 29 2 6.9 90 2.2
Pinyon mice/ Grid A 22 1 4.5 157 0.6
Molina male 10 1 10.0 71 1.4
female 12 0 0 86 0
Grid B 15 0 0 33.5 0
male 7 0 0 9 0
female 8 0 0 24.5 0
Grids A + B 37 1 2.7 190.5 0.5
male 17 1 5.9 80 1.3
female 20 0 0 110.5 0

aNo. of mice antibody-negative at first capture.
bTotal time intervals between successive captures when mice were antibody-negative, plus half the interval when mice changed from antibody-negative to antibody-positive.
cNew infections per 100 mice per month.

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