Figure 1. Early-(A) and late- stage (B) disease histopatho- logic sections of the dermis stained for acid-fast bacilli (AFB) from a patient with a Mycobacterium ulcerans infection. In A, arrows indicate necrosis of adipose tissue distant from the location of AFB, and in B, the arrow indicates predominance of extracellular bacilli and microcolonies. Patients' samples were obtained from the study conducted in Côte d'Ivoire (12). (Photos courtesy of National Center for Infectious Diseases, CDC, Atlanta, Georgia.)
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