Volume 5, Number 3—June 1999
Dispatch
Emergence of Related Nontoxigenic Corynebacterium diphtheriae Biotype mitis Strains in Western Europe
Guido Funke*, Martin Altwegg*, Lars Frommelt†, and Alexander von Graevenitz*
Table
Nontoxigenic Corynebacterium diphtheriae isolates
| Isolate no. | Date isolateda | Place of isolationb | Ribotyping patternc |
Patients sex, age (yr) | Clinical diagnosis/source | Other bacteria isolated | Underlying conditions | |
|---|---|---|---|---|---|---|---|---|
| EcoRI | PvuII | |||||||
| 2012 | 1990 | Paris | A | C | m, 6 | Endocarditis/blood culture | — | Skin lesions,scabies |
| 2410 | 2/1995 | Hamburg | A | B | m, 30 | Ulcus/lower leg | Staphylococcus aureus, Streptococcus pyogenes | Prisoner |
| 2689 | 3/1995 | Hamburg | A | A | f, 82 | Puncture/hip joint | S. epidermidis, Corynebacterium pseudodiphtherit- icum | Total hip jointendoprosthesis |
| 1682 | 9/1995 | Hamburg | A | B | m, 45 | Wound swab | S. aureus, S. pyogenes | Homelessness |
| 1935 | 3/1996 | Hamburg | A | B | m, 58 | Wound swab | S. aureus, S. pyogenes | Alcoholism, homelessness |
| 1836 | 3/1996 | Hamburg | A | B | m, 45 | Abscess/lower leg | S. aureus, S. pyogenes | Injecting drug use |
| 2661 | 3/1996 | Hamburg | A | A | m, 35 | Arthroscopy aspirate/knee joint | Peptostreptococcus prevotii,P. magnus | Osteosynthesis, arthrotomy, knee joint after trauma |
| 2658 | 4/1996 | Hamburg | A | A | f, 76 | Fistula/hip joint | S. aureus | Total hip joint endoprosthesis |
| 2674 | 5/1996 | Hamburg | A | A | f, 62 | Aspirate/hip joint | Streptococcus group C | Total hip joint endoprosthesis |
| 2670 | 7/1996 | Hamburg | A | A | f, 81 | Aspirate/knee joint | — | Total knee joint endoprosthesis |
| 2667 | 7/1996 | Hamburg | A | A | m, 23 | Swab/hip joint | Coagulase-negative staphylococci | Total hip joint endoprosthesis |
| 2413 | 11/1996 | Hamburg | A | B | m, 36 | Ulcus/lower leg | S. aureus, Streptococcus group C/G | Prisoner |
| 2446 | 12/1996 | Zurich | A | A | f, 38 | Wound/upper leg | S. aureus, S. pyogenes | Injecting drug use |
| 2464 | 1/1997 | Zurich | A | A | m, 39 | Ulcera/lower arm | Escherichia coli, S. aureus, S. pyogenes | Injecting drug use |
| 2473 | 1/1997 | Zurich | A | A | m, 38 | Ulcera/leg | E. coli, Streptococcus group C, G | Injecting drug use |
| 2475 | 1/1997 | Zurich | A | A | m, 31 | Ulcus/pretibial | Pseudomonas aeruginosa, E. coli, Streptococcus group C, G | Injecting drug use |
| 480 | 5/1997 | Bern | A | A | m, 39 | Ulcus/upper leg | S. aureus, Clostridium perfringens, mixed anaerobic flora | Injecting drug use |
aMonth/Year
bParis, France; Hamburg, Germany; Zurich, Switzerland; Bern, Switzerland.
cDNA was isolated, digested with either EcoRI or PvuII, electrophoresed, blotted, and probed for DNA. Three distinct ribopatterns emerged, each with eight bands: patterns A, B, and C.
