Volume 6, Number 2—April 2000
Synopsis
The bdr Gene Families of the Lyme Disease and Relapsing Fever Spirochetes: Potential Influence on Biology, Pathogenesis, and Evolution
David M. Roberts*, Jason A Carlyon†, Michael Theisen, and Richard T. Marconi*
Table 2
Borrelia Bdr homology groups and gene nomenclature
| Bdr subfamily designation | Species/revised gene designation | Accession or TIGR number | Previous gene names | Ref. |
|---|---|---|---|---|
| Subfamily A | ||||
| B. turicatae OZ-1 | bdrA1 | AF062395 | repA | (46) |
| B. turicatae OZ-1 | bdrA2 ,A 3,A 4 | AF128445-AF128447 | none | (25) |
| B. hermsii YOR-1 | bdrA1 ,A 2,A 3 | AF143473-AF143475 | none | (25) |
| B. hermsii HS1 | bdrA1 ,A 2 | AF143457-AF143458 | none | (25) |
| B. hermsii MAN | bdrA1 ,A 2 | AF143465, AF143467 | none | (25) |
| B. parkeri | bdrA1 | AF143455 | none | (25) |
| Subfamily B | ||||
| B. turicatae OZ-1 | bdrB1 ,B 2 ,B 3 ,B 4 ,B 5 | AF128448-AF128452 | none | (24) |
| B. hermsii MAN | bdrB1 ,B 2 ,B 3 | AF143463, AF143464, | none | (25) |
| AF143466 | ||||
| Subfamily C | ||||
| B. parkeri | bdrC 1 | AF143455 | none | (25) |
| B. hermsii MAN | bdrC 1,C 2 ,C 3 ,C 4 ,C 5 | AF143468-AF143472 | none | (25) |
| B. hermsii HS1 | bdrC 1,C 2 ,C 3 ,C 4 | AF143459-AF143462 | none | (25) |
| B. hermsii YOR-1 | bdrC 1 | AF143476 | none | (25) |
| B. parkeri | bdrC 2 | AF143456 | none | (25) |
| Subfamily D | ||||
| B. burgdorferi B31G | bdrD 1 ,D 2 ,D 3 | BBL35, BBM34, BBO34 | bdrO, bdrK, bdrM | (30) |
| B. burgdorferi B31G | bdrD 4,D 5,D 6 | BBP34, BBQ42, BBS37 | bdrA, bdrV, bdrE | (30) |
| B. burgdorferi B31 | bdrD 7 | X87201 | ORF-E (lp50 allele) | (41) |
| B. burgdorferi B31 | bdrD 8 | X87127 | ORF-E (cp30.5 allele) | (41) |
| B. burgdorferi B31 | bdrD 9 | U42599 | ORF-E (cp18 allele) | (41) |
| B. burgdorferi B31 | bdrD 1 0 | BBN34 | bdrQ | (30) |
| B. burgdorferi B31 | bdrD 1 1 | BBR35 | bdrG | (30) |
| Subfamily E | ||||
| B. burgdorferi B31G | bdrE1 ,E 2 ,E 3 | BBL27, BBN27, BBO27 | bdrP, none, bdrN | (30) |
| B. burgdorferi B31G | bdrE4 ,E 5 ,E 6 | BBR27, BBS29, BBQ34 | bdrH, bdrF, bdrW | (30) |
| B. burgdorferi 297 | bdrE1 ,E 2 | U45421, U45422 | rep+2.9-1, rep+2.9-2 | (42) |
| B. burgdorferi 297 | bdrE3, E 4 | U45423, U45424 | rep+2.9-3, rep+2.9-4 | (42) |
| B. burgdorferi 297 | bdrE5 | U45425 | rep+2.9-5 | (42) |
| B. burgdorferi 297 | bdrE6 | AF046998 | rep+2.9-8 | (45) |
| B. burgdorferi 297 | bdrE7 | AF046999 | rep+2.9-9 | (45) |
| Subfamily F | ||||
| B. afzelii DK1 | bdrF1 | Y08143 | p21 | (43) |
| B. burgdorferi B31G | bdrF1 ,F 2 ,F 3 | BBF03, BBG33, BBH13 | bdrS, bdrT, bdrU | (30) |
