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Volume 6, Number 5—October 2000

Research

Testing Umbilical Cords for Funisitis due to Treponema pallidum Infection, Bolivia

Jeannette Guarner*Comments to Author , Karen Southwick*, Patricia Greer*, Jeanine Bartlett*, Martha Fears*, Ana Santander†, Stanley Blanco†, Victoria Pope*, William Levine*, and Sherif Zaki*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †MotherCare, La Paz, Bolivia

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Table 1

Inflammation, necrosis, and treponemes in umbilical cords from infants with congenital syphilis, Bolivia

Specimens with Specimens without
treponemes: treponemes: Odds ratio
Umbilical cord Histologic No. pos. /No. tested No. pos. /No. tested (95% confidence
structure parameter (%) (N = 9) (%) (N = 79) intervals)
Umbilical arterya Acute inflammation 3/8 (38) 6/78 (8) 7.2 (1.0-49)
Chronic inflammation 3/8 (38) 4/78 (5) 11.1 (1.5-89)
Necrosis 2/8 (25) 0/78 (0) undefinedb
Normal 3/8 (38) 65/78 (83) 0.1 (0.0-0.4)
Umbilical vein Acute inflammation 7/9 (78) 15/78 (19) 14.7 (2.4-115)
Chronic inflammation 5/9 (56) 5/78 (6) 18.3 (3.0-125)
Necrosis 5/9 (56) 0/78 (0) undefinedc
Normal 1/9 (11) 50/78 (64) 0.1 (0.0-0.6)
Wharton's jelly Acute inflammation 8/9 (89) 12/79 (15) 44.7 (4.8-1,043)
Chronic inflammation 5/9 (56) 4/79 (5) 23.4 (3.6-178)
Normal 1/9 (11) 6/79 (8) 0.03 (0.0-0.3)

aThe umbilical artery was missing in two specimens, and the umbilical vein was missing in another. bp=0.01 c<0.001

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