Volume 7, Number 1—February 2001
Research
Preoperative Drug Dispensing as Predictor of Surgical Site Infection1
Keith S. Kaye*
, Kenneth Sands*, James G. Donahue†, K. Arnold Chan†, Paul Fishman‡, and Richard Platt†
, Kenneth Sands*, James G. Donahue†, K. Arnold Chan†, Paul Fishman‡, and Richard Platt†Table 1
Characteristics of the study population
| Controls | Odds ratioa | |||
|---|---|---|---|---|
| Variable | Cases (no.=191) | (no.=372) | p value | (95% CI) |
| Mean age (yrs) | 51.2 | 51.5 | NA | NA |
| Male sex (%) | 91 (47.6) | 182 (48.9) | NA | NA |
| NNISb wound class, | 8 (4.2) | 13 (3.5) | NA | NA |
| contaminated or infected (%) | ||||
| Surgical Specialty(%) General Cardiac Orthopedic Plastic Urologic Vascular Gynecologic Neurosurgical Other | 54 (28.3) 41 (21.5) 31 (16.2) 17 (8.9) 14 (7.3) 10 (5.2) 5 (2.6) 4 (2.1) 15 (7.9) | 107 (28.8) 78 (21.0) 63 (16.9) 30 (8.1) 27 (7.3) 19 (5.1) 10 (2.7) 8 (2.2) 30 (7.8) | NA | NA |
| General anesthesia (%) | 132 (69.1) | 222 (59.7) | 0.004 | 2.19 (1.29,3.72) |
| Median duration of surgery (min) (IQRc) | 105 (55-211) | 83 (40-154) | <0.001d | 1.75 (1.34,2,29)d |
| Emergent procedure (%) | 11 (5.8) | 10 (2.7) | 0.07 | 2.21 (0.94,5.21) |
| ASA score (%) Missing 1 2 3 4 5 | 30 (15.7) 32 (16.8) 62 (32.5) 59 (30.9) 8 (4.2) 0 | 80 (21.5) 83 (22.3) 130 (34.9) 74 (19.9) 5 (1.4) 0 | 0.002f | 2.0 (1.4, 2.9)f |
| Chronic disease score Median (IQR) | 2,219 (1,101-5,673) | 1,641 (809-3,588) | 0.09 | NA |
aOR=odds ratio.
bNNIS=National Nosocomial Infection Surveillance System.
cIQR=Interquartile range.
dValues are for duration as a 6-level ordinal variable. Risk is per-unit increase in duration category.
eASA=American Society of Anesthesiologists phycial status scale.
fASA as a four-level ordinal variable, excluding missing values. Risk is per-unit increase in ASA category, missing values excluded.
