Skip directly to search Skip directly to A to Z list Skip directly to site content
CDC Home

Volume 7, Number 1—February 2001

Research

Preoperative Drug Dispensing as Predictor of Surgical Site Infection1

Keith S. Kaye*Comments to Author , Kenneth Sands*, James G. Donahue†, K. Arnold Chan†, Paul Fishman‡, and Richard Platt†
Author affiliations: *Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA; †Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA; ‡Group Health Cooperative of Puget Sound, Seattle, Washington, USA; *†the Eastern Massachusetts CDC Prevention Epicenter

Main Article

Table 1

Characteristics of the study population

Controls Odds ratioa
Variable Cases (no.=191) (no.=372) p value (95% CI)
Mean age (yrs) 51.2 51.5 NA NA
Male sex (%) 91 (47.6) 182 (48.9) NA NA
NNISb wound class, 8 (4.2) 13 (3.5) NA NA
contaminated or infected (%)
Surgical Specialty(%)
 General
 Cardiac
 Orthopedic
 Plastic
 Urologic
 Vascular
 Gynecologic
 Neurosurgical
 Other 54 (28.3)
41 (21.5)
31 (16.2)
17 (8.9)
14 (7.3)
10 (5.2)
5 (2.6)
4 (2.1)
15 (7.9) 107 (28.8)
78 (21.0)
63 (16.9)
30 (8.1)
27 (7.3)
19 (5.1)
10 (2.7)
8 (2.2)
30 (7.8) NA NA
General anesthesia (%) 132 (69.1) 222 (59.7) 0.004 2.19 (1.29,3.72)
Median duration of surgery (min) (IQRc) 105 (55-211) 83 (40-154) <0.001d 1.75 (1.34,2,29)d
Emergent procedure (%) 11 (5.8) 10 (2.7) 0.07 2.21 (0.94,5.21)
ASA score (%)
 Missing
 1
 2
 3
 4
 5 30 (15.7)
32 (16.8)
62 (32.5)
59 (30.9)
8 (4.2)
0 80 (21.5)
83 (22.3)
130 (34.9)
74 (19.9)
5 (1.4)
0 0.002f 2.0 (1.4, 2.9)f
Chronic disease score
Median (IQR) 2,219 (1,101-5,673) 1,641
(809-3,588) 0.09 NA

aOR=odds ratio.
bNNIS=National Nosocomial Infection Surveillance System.
cIQR=Interquartile range.
dValues are for duration as a 6-level ordinal variable. Risk is per-unit increase in duration category.
eASA=American Society of Anesthesiologists phycial status scale.
fASA as a four-level ordinal variable, excluding missing values. Risk is per-unit increase in ASA category, missing values excluded.

Main Article

1This study was presented in part at the Society for Healthcare Epidemiology of America annual meeting, San Francisco, California, April 1999, and at the 4th Decennial International Conference on Nosocomial and Health Care-Associated Infections, Atlanta, Georgia, March 2000.

Top of Page

USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO