Emerging Infectious Disease ISSN: 1080-6059

Lack of Evidence of Endogenous Avian Leukosis Virus and Endogenous Avian Retrovirus Transmission to Measles Mumps Rubella Vaccine Recipients

Althaf I. Hussain*, Vedapuri Shanmugam*, William M. Switzer*, Shirley X. Tsang*, Aly Fadly†, Donald Thea‡, Rita Helfand*, William J. Bellini*, Thomas M. Folks*, and Walid Heneine*

Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Avian Disease and Oncology Laboratory, U.S. Department of Agriculture, East Lansing, Michigan, USA; ‡Harvard Institute for International Development, Cambridge, Massachusetts, USA

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Figure 3

Reverse transcriptase-polymerase chain reaction analysis of sera from measles mumps rubella (MMR) vaccine recipients for the presence of avian leukosis virus (ALV) (A) and endogenous avian retrovirus (EAV) (B) RNA. Lanes 1-10, samples from MMR vaccine recipients. NC, negative control, uninfected human serum; PC, positive control, culture supernatant from Rous-associated virus 0 (RAV-0) infected 15B1 chick embryo fibroblasts.

Figure 3. Reverse transcriptase-polymerase chain reaction analysis of sera from measles mumps rubella (MMR) vaccine recipients for the presence of avian leukosis virus (ALV) (A) and endogenous avian retrovirus (EAV) (B) RNA. Lanes 1-10, samples from MMR vaccine recipients. NC, negative control, uninfected human serum; PC, positive control, culture supernatant from Rous-associated virus 0 (RAV-0) infected 15B₁ chick embryo fibroblasts.

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