Skip directly to search Skip directly to A to Z list Skip directly to site content
CDC Home

Volume 7, Number 1—February 2001

Research

Persistence and variability of Stenotrophomonas maltophilia in Cystic Fibrosis Patients, Madrid, 1991-1998

Sylvia Valdezate*†, Ana Vindel†, Luis Maiz*, Fernando Baquero*, Hector Escobar*, and Rafael Cantón*Comments to Author 
Author affiliations: *Hospital Ramón y Cajal, Madrid, Spain; †Centro Nacional de Microbiología, Instituto Carlos III, Madrid, Spain

Main Article

Table

Demographic characteristics and co-colonization status of cystic fibrosis patients with Stenotrophomonas maltophilia infection or colonization

Characteristics SM-SEa (14 patients) SM-REb (11 patients)
Gender
Male 8 5
Female 6 6
Patient genotyped 11 9
Homozygous F508 8 3
Heterozygous F508 3 5
Other 0 1
Mean age at first S. maltophilia isolation (SD, years) 13.4 (7.3) 16.7 (7.4)
FEV1 measured 11 10
FEV1 (% predicted) before S. maltophilia recovery (Mean [SD]) 68.7 (29.6) 74.2 (28.3)
>100 2 1
70-99 3 5
40-69 4 3
< 40 2 1
FEV1 (% predicted) after S. maltophilia recovery (Mean [SD]) 63.8 (20.7) 62.9 (24.2)
ABPAc condition 2 1
Death (%) 4 (28.5) 2 (18.2)
S. maltophilia bacterial counts (geometric mean, cfu/mL) 8.4 x 104 d 2.9 x 108 d
Pseudomonas aeruginosa detected (%) 12 (85.7) 9 (81.8)
Aspergillus detected (%) 7 (50.0) 7 (63.6)
S. maltophilia co-colonization with:e
Only S. maltophilia detected (%) 1 (7.1) 1 (9.1)
P. aeruginosa (%) 8 (57.1) 3 (27.2)
Staphylococcus aureus (%) 6 (42.8) 3 (27.2)
Burkholderia cepacia (%) 1 (7.1) 1 (9.1)
Aspergillus spp. (%) 1 (7.1) 3 (27.2)
Candida (%) 3 (21.4) 2 (18.2)

aSM-SE = CF patients with a single episode of S. maltophilia colonization.
bSM-RE: CF patients with repeated episodes of S. maltophilia colonization.
cABPA: allergic bronchopulmonary aspergillosis.
dp<0.05 comparing both groups.
ePatients in the SM-RE group colonized with organisms in addition to S. maltophilia. When different cocolonizations occurred in the same patient, we recorded only the co-colonization that was at least twice as frequent.

Main Article

Top of Page

USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO