Pathologic Studies of Fatal Cases in Outbreak of Hand, Foot, and Mouth Disease, Taiwan
Wun-Ju Shieh* , Shih-Ming Jung†, Chuen Hsueh†, Tseng-Tong Kuo†, Anthony Mounts*, Umesh Parashar*, Chen Fu Yang*, Jeannette Guarner*, Thomas G. Ksiazek*, Jacqueline Dawson*, Cynthia Goldsmith*, Gwong-Jen J. Chang*, Steve M. Oberste*, Mark A. Pallansch*, Larry J. Anderson*, Sherif R. Zaki*, and the Epidemic Working Group
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Chang Gung Memorial Hospital, Tauyuan, Taiwan, Republic of China; ¹Epidemic Working Group at Centers for Disease Control and Prevention: Jim Alexander, Betty Brown, David Shay, Patricia Greer, Charles Humphrey, Tim Morken; Tara Ferebee-Harris.
Figure 1. A). Positive immunostaining of EV71 antigens in neuron and neuronal process. Original magnification, X158. B). Positive immunostaining of EV71 antigens in necrotic area. Original magnification, X158. C). An array of picornavirus particles in a neuron (electron micrograph).
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