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Volume 7, Number 2—April 2001
4th Decennial International Conference on Nosocomial and Healthcare-Associated Infections

State of the Art

Increasing Resistance to Vancomycin and Other Glycopeptides in Staphylococcus aureus

Fred C. Tenover*, James W. Biddle*, and Michael V. Lancaster†
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †Bright Ideas, Monterey, California, USA

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Table 3

Resistance patterns of staphylococcal study isolates to commonly tested antimicrobial agentsa

Isolate (source) Resistant or intermediateb Susceptible
Staphylococcus aureus (Michigan) Cd, Cip, E, Gm, Ox, P C, L, Q-D, Rif, SXT, T
S. aureus (New Jersey) Cd, Cip, E, Ox, P, Rif C, Gm, L, Q-D, SXT, T
S. aureus (New York) Cip, E, Ox, P, Rif C, Cd, Gm, L, Q-D, SXT, T
S. aureus (Illinois) C(I), Cd, Cip, E, Ox, P, Rif L, Q-D, SXT, T
S. aureus (Germany) Ak, Cd, Cip, E, Gm, Ox, P, Te Fu, Ne
S. aureus (France, LIM-2) C, Cd, Cip, E, Ox, P, Rif, Te C, L, Q-D, SXT

aAs determined using the broth microdilution reference method. bAbbreviations: C: chloramphenicol; Cd: clindamycin; Cip: ciprofloxacin; E: erythromycin; Fu: fusidic acid; Gm: gentamicin; L: linezolid; Ne: netilmycin; Ox: oxacillin; P: penicillin; Q-D, quinupristin-dalfopristin; Rif: rifampin; SXT: trimethoprim/ sulfamethoxazole; T: tetracycline. (I): intermediate. Based on data presented in references 20, 26, 32, and unpublished observations from CDC.

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