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Volume 7, Number 2—April 2001
4th Decennial International Conference on Nosocomial and Healthcare-Associated Infections


The Impact of Hospital-Acquired Bloodstream Infections

Richard P. WenzelComments to Author  and Michael B. Edmond
Author affiliations: Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA

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Table 2

Central venous catheter technology and nosocomial bloodstream infections and deaths

CVCa-related remaining if new
Attributable deaths from catheters prevent No. of lives
 mortality rate (%) bloodstream infectionsb 45% of deaths saved
15 10,500 5,755 4,745
20 14,000 7,700 6,300
25 17,500 9,625 7,875
30 21,000 11,550 9,450

aCVC = Central venous catheter.
bAssumptions in this analysis: 200,000 bloodstream infections/year, 35% attributed to CVCs, 45% prevented with antibiotic-bonded catheters. Previous studies showed 175,000-350,000 nosocomial bloodstream infections/yr, 70% of which were related to central venous catheters; 90% of central venous catheter-related bloodstream infections prevented with antibiotic bonded catheters (11).

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