Volume 7, Number 2—April 2001
THEME ISSUE
4th Decennial International Conference on Nosocomial and Healthcare-Associated Infections
State of the Art
Molecular Approaches to Diagnosing and Managing Infectious Diseases: Practicality and Costs
Michael A. Pfaller
Table 2
Noncommercial nucleic acid-based tests for clinically important viral and bacterial pathogensa
| Organism | Specimen type | Clinical indication |
|---|---|---|
| Epstein-Barr virus (EBV) | Cerebrospinal fluid (CSF) | EBV lymphoproliferative disorder |
| Herpes simplex virus (HSV) types 1 and 2 | CSF Vitreous humor | Encephalitis |
| Varicella-zoster virus (VZV) | Various tissues | VZV reactivation |
| JC virus | CSF | Progressive multifocal leukoencephalopathy |
| Enterovirus | CSF | Aseptic meningitis |
| Parvovirus B19 | Amniotic fluid Serum | Hydrops fetalis Anemia |
| Adenovirus | Urine Tissues Blood | Immunocompromised patients, transplant recipients |
| Ehrlichia | Blood | Human granulocytic and monocytic ehrlichiosis |
| Bordetella pertussis | Nasopharyngeal aspirate | Whooping cough |
| Legionella pneumophila | Respiratory | Atypical pneumonia |
| Chlamydia pneumoniae | Respiratory | Atypical pneumonia |
| Mycoplasma pneumoniae | Respiratory | Atypical pneumonia |
| Helicobacter pylori | Gastric fluid Stool | Peptic ulcer disease |
aAll tests use polymerase chain reaction. The list is not all-inclusive.
