Volume 7, Number 6—December 2001
Research
Reduced Fluoroquinolone Susceptibility in Salmonella enterica Serotypes in Travelers Returning from Southeast Asia
Antti Hakanen*†
, Pirkko Kotilainen†, Pentti Huovinen*, Hans Helenius‡, and Anja Siitonen§
, Pirkko Kotilainen†, Pentti Huovinen*, Hans Helenius‡, and Anja Siitonen§Table 2
Number and source of 629 Salmonella isolates from Finnish travelers and the annual numbers of isolates with reduced ciprofloxacin susceptibility (MIC >0.125 µg/mL), 1995 to 1999
| Isolates with reduced ciprofloxacin susceptibility |
||||||||
|---|---|---|---|---|---|---|---|---|
| Yeara |
||||||||
| Geographic area | All isolates | 1995 (102) | 1996 (216) | 1997 (107) | 1998 (102) | 1999 (102) | Total (% of all isolates) | p valueb |
| Africa | 86 | 0 | 0 | 2 | 2 | 0 | 4 (4.7) | 0.144 |
| America | 27 | 0 | 0 | 0 | 0 | 1 | 1 (3.7) | 0.132 |
| Asia | 292 | 3 | 6 | 8 | 14 | 18 | 49 (16.8) | <0.001 |
| Southeast Asia | 147 | 1 | 1 | 6 | 10 | 18 | 36 (24.5) | <0.001 |
| Middle East | 93 | 2 | 5 | 1 | 2 | 0 | 10 (10.8) | 0.706 |
| Other areas | 52 | 0 | 0 | 1 | 2 | 0 | 3 (5.8) | 0.119 |
| Europe | 222 | 1 | 4 | 1 | 0 | 5 | 11 (5.0) | 0.079 |
| Mediterranean area | 78 | 1 | 2 | 1 | 0 | 1 | 5 (6.4) | 0.801 |
| Canary Islands | 60 | 0 | 1 | 0 | 0 | 3 | 4 (6.7) | 0.147 |
| Other parts | 84 | 0 | 1 | 0 | 0 | 1 | 2 (2.4) | 0.205 |
| Total | 629c,d | 4c | 10c | 11c | 17c,e | 24c | 66c,e (10.5) | <0.001 |
aThe annual numbers of all isolates from Finnish travelers studied in parentheses.
bThe differences between years were modeled as a trend over years in these analyses. p value shows the statistical significance of this trend.
cSum of the numbers written in bold.
dTwo isolates of unknown origin included.
eOne isolate of unknown origin included.
