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Volume 8, Number 1—January 2002

Research

Changes in Predominance and Diversity of Genomic Subtypes of Bordetella pertussis Isolated in the United States, 1935 to 1999

Terri Hawes Hardwick, Pamela Cassiday, Robbin S. Weyant, Kristine M. Bisgard, and Gary N. SandenComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA;

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Table

Frequencies of the most prevalent pulsed-field gel electrophoresis (PFGE) profiles of Bordetella pertussis strains isolated in the United States from 1935 to 1999

PFGE Total US n=1,333 Total US w/o Cinn n=853 1935-1965 n=16 1966-1985 n=127 1986-1999 n=1,190 1986-1999 w/o Cinn n=710
2 9.6 4.3 - - 10.8 5.4
3a 2.4 1.3 - 2.4 2.4 1.1
4a 3.7 0.4 - 0.8 4 0.3
6a 3.1 0.1 - 0.8 3.4 0.1
7 1.4 1.8 - - 1.6 2.1
8 2 - - - 2.2 -
10a 33.3 33.9 - 0.8 37.3 40.8
13 9.2 14.1 - - 10.3 17
14b 1.6 2.6 18.8 4.7 1.1 1.8
15a 2.6 0.8 - 1.6 2.7 0.8
17a 0.8 0.8 - 3.1 0.5 0.4
20b 1 1.5 6.3 8.7 0.2 0.1
21a 2.3 2.2 - 3.9 2.2 2
27a 7.1 9.3 - 13.4 6.5 8.8
37 0.7 1 - - 0.8 1.3
46 1.1 1.8 - - 1.3 2.2
52 0.4 0.6 - 3.9 - -
53a 0.3 0.5 - 1.6 0.2 -
62 1.1 1.8 - 11.8 - -
64b 1.4 2.2 18.8 9.4 0.3 0.6
66a 0.6 0.9 - 5.5 0.1 0.1
69 0.8 1.2 - 7.9 - -
71c 0.2 0.4 12.5 0.8 - -
74b 0.5 0.8 6.3 3.9 0.1 0.1
75 0.2 0.4 - 2.4 - -
82 2.1 3.3 - - 2.4 4
Total 89.5 88 62.7 87.4 90.4 89

aPFGE profile spans second and third time periods.

bPFGE profile spans all three time periods.

cPFGE profile spans first and second time periods.

CINN = Cinncinnati, Ohio, data.

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