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Volume 8, Number 10—October 2002
THEME ISSUE
Bioterrorism-related Anthrax

Bioterrorism-related Anthrax

Adherence to Antimicrobial Inhalational Anthrax Prophylaxis among Postal Workers, Washington, D.C., 2001

Mariaelena D. Jefferds*Comments to Author , Kayla Laserson*, Alicia M. Fry*, Sharon L. Roy*, James Hayslett*, Laurence Grummer-Strawn*, Laura Kettel-Khan*, Anne Schuchat*, and selected members of the Centers for Disease Control and Prevention Anthrax Adherence Team1
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA;

Main Article

Table 5

Predictors of discontinued Therapy (n=45) compared with full adherence (n=98), Washington, D.C., 2001a

Predictor covariates Adjusted, OR (95% CI) p value
Age 18-44 y 6.7 (2.6 to 17.3) <0.05
Perceived riskb High 0.1 (0.01 to 0.8) <0.05
Some 0.4 (0.1 to 3.0) n.s.
None ref -
Adverse effectsc A lot 20.4 (3.0 to 140.1) <0.05
Some 1.7 (0.6 to 5.1) n.s.
Not at all ref -
Physical signs of stressd 5-11 signs 0.02 (0.003 to 0.2) <0.05
1-4 signs 0.3 (0.1 to 1.1) n.s.
0 signs Ref -
Anxietye Yes 3.5 (1.1 to 10.9) <0.05

aOR, odds ratio; 95% CI, 95% confidence interval; n.s., not statistically significant; ref, referent.
bPerceived risk of breathing in B. anthracis spores during exposure period October 12-21, 2001.
cReported how much side effects affected their life.
dPhysical signs of stress included fatigue, headaches, chest pain, rapid heartbeat, unplanned changes in weight, less or difficulty sleeping, muscle tremors or twitches, difficulty or rapid breathing, elevated blood pressure, nausea or vomiting, and dizziness or lightheadedness.
eReported they experienced anxiety since anthrax events started.  Anxiety was one of 22 listed symptoms of stress on our questionnaire.

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1 The following members of the team were involved in the Washington, D.C., area response: Theodies Mitchell, Charlie Chamberlain, Arlene Shaw, Margaret Patterson, Chang Lee, Daryle Hardge, Veronica McCant, Robert Fireall, Colleen Crowley, Sandra Mattson, Margaret Tipple, Suzanne Lebovit, Pat Cook, Valerie J. Curry, Kelly Holton, Susan L. Lukacs, Julia C. Rhodes, Cindy R. Friedman, Holly A. Williams, Michelle G. Goveia, Leigh Winston, Heather Burke, Veronica Alvarez, Gail M. Stennies, Ernest E. Smith, Brigette Finkelstein, Julia Smith, Bobbie Person, Ian Williams, Wanda Walton, Nick Deluca, Regina Bess, Gabrielle Benenson, Kathleen Hutchins, and Luetta Schneider.

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