Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping

Tuberculosis Genotyping Network, United States

Statewide Molecular Epidemiology of Mycobacterium tuberculosis Transmission in a Moderate- to Low-Incidence State: Are Contact Investigations Enough?

Wendy A. Cronin* , Jonathan E. Golub*, Monica J. Lathan†, Leonard N. Mukasa*, Nancy Hooper*, Jafar H. Razeq*, Nancy G. Baruch*, Donna Mulcahy‡, William H. Benjamin§, Laurence S. Magder¶, G. Thomas Strickland¶, and William R. Bishai#

Author affiliations: *Maryland Department of Health and Mental Hygiene, Baltimore, Maryland, USA; †American Public Health Association, Washington, D.C., USA; ‡Alabama Department of Public Health, Montgomery, Alabama, USA; §University of Alabama at Birmingham, Birmingham, Alabama, USA; ¶University of Maryland—Baltimore, Maryland, USA; #The Johns Hopkins University, Baltimore, Maryland, USA;

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Table 2

Selected characteristics of culture-positive patients with comparison between categories

	No. patients with recent TB (%) (N=115)	No. patients with probable recent TB (%) (n=82)	No. patients with reactivated TB (%) (n=788)	p value	p value
Characteristic	Group A	Group B	Group C	A vs. B	A vs. C
Residence
Baltimore City	57 (50.0)	38 (46.3)	157 (19.9)	0.66	<0.001
Other state jurisdictions	58 (50.0)	44 (53.7)	631 (80.1)
Age group (yrs)
0–14a	6 (5.2)	3 (3.7)	5 (0.6)	<0.001	<0.001
15–24	21 (18.3)	7 (8.5)	86 (10.9)
25–44	46 (40.0)	27 (32.9)	275 (34.9)
45–64	33 (28.7)	20 (24.3)	178 (22.6)
>65	9 (7.8)	25 (30.4)	244 (31.0)
Race/ethnicity
White, non-Hispanic	20 (17.4)	17 (20.7)	162 (20.6)	0.03	<0.001
Black, non-Hispanic	89 (77.4)	51 (62.2)	341 (43.3)
Hispanic	1 (0.9)	5 (6.1)	84 (10.7)
Asian	5 (4.3)	9 (11.0)	200 (25.4)
Native American	0	0	1 (0.1)
Country of birth
United States	105 (91.3)	66 (80.5)	360 (45.7)	0.03	<0.001
Other	10 (8.7)	16 (19.5)	428 (54.3)
Long-term care resident
Yes	7 (6.1)	5 (3.3)	25 (3.2)	1.00	0.11
No	108 (93.9)	77 (96.7)	763 (96.8)
Homeless
Yes	18 (15.7)	8 (9.8)	23 (2.9)	0.22	<0.001
No	97 (84.3)	74 (90.2)	765 (97.1)
Prison resident
Yes	13 (11.3)	10 (13.1)	21 (2.7)	0.85	<0.001
No	102 (88.7)	72 (86.9)	767 (97.3)
Uses illegal drugs or abuses alcohol
Yes	53 (46.0)	30 (36.6)	76 (9.6)	0.18	<0.001
No	62 (54.0)	58 (63.4)	712 (90.4)
HIV-infected
Yes	28 (24.3)	19 (23.2)	75 (9.5)	0.85	<0.001
No	87 (75.7)	63 (76.8)	713 (90.5)
aIncludes one child < 6 years old without a known source patient; the case was classified as recent based on age.

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