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Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping

Tuberculosis Genotyping Network, United States

Molecular Epidemiology of Multidrug-Resistant Tuberculosis, New York City, 1995–1997

Sonal S. Munsiff*†Comments to Author , Trina Bassoff*, Beth Nivin*, Jiehui Li*, Anu Sharma*, Pablo Bifani‡, Barun Mathema‡, Jeffrey Driscoll§, and Barry N. Kreiswirth‡
Author affiliations: *New York City Department of Health, New York, New York, USA; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA; ‡Public Health Research Institute TB Center, Newark, New Jersey, USA; §Wadsworth Center, Albany, New York, USA;

Main Article

Table 1

Comparison of social and demographic characteristics of multidrug-resistant (MDR) tuberculosis patients and non-multidrug-resistant tuberculosis patients, New York City, 1995-1997

MDR (n=241) Non-MDR (n=4,714)
Characteristic No. % No. % p value
Yr of diagnosis
1995 106 44.0 1,816 38.5 0.0898
1996 81 33.6 1,586 33.6 0.9912
1997 54 22.4 1,312 27.8 0.0660
Median age (range), yrs 41 (5–85) 41 (0–100) 0.3071
Male sex 147 61.0 3,020 64.1 0.3333
U.S.-born 166 68.9 2,483 52.7 <0.001
HIV serostatus
Positive 128 53.1 1,478 31.4 <0.001
Negative 75 31.2 1,759 37.3 0.0521
Unknown 38 15.8 1,477 31.3 <0.001
Race/ethnicity
Asian 24 10.0 817 17.3 0.0029
Hispanic 75 31.1 1,266 26.9 0.1461
Black non-Hispanic 105 43.6 2,089 44.3 0.8200
White non-Hispanic 37 15.4 542 11.5 0.0692
Health-care worker 15 6.2 109 2.3 0.0001
Homeless 28 11.6 344 7.3 0.0130
Injection drug user 33 13.7 275 5.8 <0.001
Disease site
Pulmonary only 176 73.0 3,397 72.1 0.7440
Extra-pulmonary only 35 14.5 894 19.0 0.0848
Pulmonary + extra-pulmonary 30 12.5 423 9.0 0.0679
Specimen AFB smear-positivea 141 68.5 2,129 55.7 0.0003
Cavitary lesion(s)b 47 22.8 740 19.4 0.2247

aRespiratory specimen during the 30 days after initial specimen for bacteriologic test was taken. Excludes those who had only extrapulmonary disease.
bExcludes those with extrapulmonary disease only.

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