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Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping

Tuberculosis Genotyping Network, United States

Genotyping Analyses of Tuberculosis Cases in U.S.- and Foreign-Born Massachusetts Residents

Sharon Sharnprapai*Comments to Author , Ann C. Miller*, Robert Suruki*, Edward Corkren*, Sue Etkind*, Jeffrey Driscoll†, Michael McGarry†, and Edward Nardell*‡
Author affiliations: *Massachusetts Department of Public Health, Boston, Massachusetts, USA; †New York State Department of Health, Wadsworth Center, Albany, New York, USA; ‡Harvard Medical School, Boston, Massachusetts, USA;

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Table 2

Demographic characteristics of U.S.-born and foreign-born tuberculosis (TB) case-patientsa

Demographics Foreign-born (%)
n=684 U.S.-born (%)
n=299 Odds ratio and 95% confidence interval (CI) p value
Sex
Male 380 (56) 183 (61) 0.80 (95% CI 0.60, 1.06) p=0.11
Female 304 (44) 117 (39)
Age groupb
<1–24 106 (16) 23 (8) 1.0
25–44 327 (48) 75 (25) 1.06 (95% CI 0.61,1.83) p=0.83
45–64 148 (22) 93 (31) 2.90 (95% CI 1.67,5.04) p<0.01
>65 103 (15) 108 (36) 4.83 (95% CI 2.77,8.47) p<0.01
Site of diseaseb
Pulmonary 452 (66) 238 (80) 0.50 (95 %CI 0.36,0.70) p<0.01
Extrapulmonary 232 (34) 61 (20)
HIV status
Positive 59 (9) 31 (10) 0.75 (95% CI 0.44,1.30) p= 0.28
Negative 177 (26) 70 (23)
Unknown 449 (66) 198 (66)
Homeless in past yearb
Yes 16 (2) 38 (13) 0.16 (95% CI 0.09,0.31) p<0.01
No 666 (97) 258 (86
Unknown 2 (<1) 3 (1)
Drug use in past
Yearb,c
Yes 6 (<1) 27 (9) 0.08 (95% 0.03,0.21) p<0.01
No 611 (89) 221 (74)
Unknown 67 (10) 51 (17)
Excessive alcohol use in past yearb
Yes 34 (5) 74 (25) 0.14 (95% CI 0.09,0.22) p<0.01
No 577 (84) 176 (59)
Unknown 73 (11) 49 (16)

aDefinitions of homeless, dug use and alcohol use are based on criteria established by the Centers for Disease Control and Prevention.
b Significant difference observed between U.S.-born and foreign-born at p<0.01.
cIncludes both injecting and noninjecting drug users.

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