Volume 8, Number 11—November 2002
THEME ISSUE
Tuberculosis Genotyping
Tuberculosis Genotyping Network, United States
Genotyping Analyses of Tuberculosis Cases in U.S.- and Foreign-Born Massachusetts Residents
Sharon Sharnprapai*
, Ann C. Miller*, Robert Suruki*, Edward Corkren*, Sue Etkind*, Jeffrey Driscoll†, Michael McGarry†, and Edward Nardell*‡
, Ann C. Miller*, Robert Suruki*, Edward Corkren*, Sue Etkind*, Jeffrey Driscoll†, Michael McGarry†, and Edward Nardell*‡Table 2
Demographic characteristics of U.S.-born and foreign-born tuberculosis (TB) case-patientsa
| Demographics | Foreign-born (%) n=684 | U.S.-born (%) n=299 | Odds ratio and 95% confidence interval (CI) | p value |
|---|---|---|---|---|
| Sex | ||||
| Male | 380 (56) | 183 (61) | 0.80 (95% CI 0.60, 1.06) | p=0.11 |
| Female | 304 (44) | 117 (39) | ||
| Age groupb | ||||
| <1–24 | 106 (16) | 23 (8) | 1.0 | |
| 25–44 | 327 (48) | 75 (25) | 1.06 (95% CI 0.61,1.83) | p=0.83 |
| 45–64 | 148 (22) | 93 (31) | 2.90 (95% CI 1.67,5.04) | p<0.01 |
| >65 | 103 (15) | 108 (36) | 4.83 (95% CI 2.77,8.47) | p<0.01 |
| Site of diseaseb | ||||
| Pulmonary | 452 (66) | 238 (80) | 0.50 (95 %CI 0.36,0.70) | p<0.01 |
| Extrapulmonary | 232 (34) | 61 (20) | ||
| HIV status | ||||
| Positive | 59 (9) | 31 (10) | 0.75 (95% CI 0.44,1.30) | p= 0.28 |
| Negative | 177 (26) | 70 (23) | ||
| Unknown | 449 (66) | 198 (66) | ||
| Homeless in past yearb | ||||
| Yes | 16 (2) | 38 (13) | 0.16 (95% CI 0.09,0.31) | p<0.01 |
| No | 666 (97) | 258 (86 | ||
| Unknown | 2 (<1) | 3 (1) | ||
| Drug use in past | ||||
| Yearb,c | ||||
| Yes | 6 (<1) | 27 (9) | 0.08 (95% 0.03,0.21) | p<0.01 |
| No | 611 (89) | 221 (74) | ||
| Unknown | 67 (10) | 51 (17) | ||
| Excessive alcohol use in past yearb | ||||
| Yes | 34 (5) | 74 (25) | 0.14 (95% CI 0.09,0.22) | p<0.01 |
| No | 577 (84) | 176 (59) | ||
| Unknown | 73 (11) | 49 (16) | ||
aDefinitions of homeless, dug use and alcohol use are based on criteria established by the Centers for Disease Control and Prevention.
b Significant difference observed between U.S.-born and foreign-born at p<0.01.
cIncludes both injecting and noninjecting drug users.
