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Volume 8, Number 12—December 2002


Legionnaires’ Disease at a Dutch Flower Show: Prognostic Factors and Impact of Therapy

Kamilla D. Lettinga*Comments to Author , Annelies Verbon*, Gerrit-Jan Weverling*, Joop F.P. Schellekens†, Jeroen W. Den Boer†‡, Ed P.F. Yzerman§, Jacobus Prins¶, Wim G. Boersma#, Ruud J. van Ketel*, Jan M. Prins*, and Peter Speelman*
Author affiliations: *Academic Medical Center, Amsterdam, the Netherlands; †National Institute of Public Health and the Environment, Bilthoven, the Netherlands; ‡Municipal Health Service Zuid-Kennemerland, Haarlem, the Netherlands; §Regional Laboratory of Public Health Haarlem, Haarlem, the Netherlands; ¶Westfries Gasthuis, Hoorn, the Netherlands; #Medical Center Alkmaar, Alkmaar, the Netherlands;

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Table 2

Multivariate analysis of factors determining outcome

Prognostic factora Odds ratio (95% CI)b
(n=141) p value
Smoking 2.5 (1.1 to 5.6) 0.03
Dyspnea at presentation 2.1 (0.9 to 4.8) 0.09
Temperature >38.5°C 2.9 (1.0 to 8.6) 0.05
Plasma creatinine >100 µmol/L 2.0 (0.9 to 4.6) 0.11
Bilateral infiltrates 4.2 (1.7 to 10.3) 0.002
Pleural effusion 3.4 (0.99 to 11.6) 0.053

aPrognostic factors with p≤ 0.05 in the univariate analysis were entered. Factors with p value >0.2 in the multivariate analysis were excluded.
bCI, confidence interval.

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