Emerging Infectious Disease ISSN: 1080-6059

Rat-to-Human Transmission of Cowpox Infection

Tom F.W. Wolfs*

, Jaap A. Wagenaar†, Hubert G.M. Niesters‡, and Albert D.M.E. Osterhaus‡

Author affiliations: *Wilhelmina Children’s Hospital/University Medical Center, Utrecht, the Netherlands; †Utrecht University, Utrecht, the Netherlands; ‡University Hospital, Rotterdam, the Netherlands;

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Figure 2

Phylogenetic tree of nucleotide sequences of 163-bp Orthopoxvirus fusion gene amplicons from the patient and rat (head and paw), Cowpox virus, Vaccinia virus (strain Ankara and WR), Camelpox virus, Monkeypox virus, Variola virus, and Ectromelia virus (Mousepox virus). The nucleotide sequences were aligned by using BioEdit software package (T. Hall, Dept. of Microbiology, Raleigh, NC). Phylogenetic relationships were determined by using the Lasergene software packages (DNASTAR Inc., Madison, WI).

Figure 2. Phylogenetic tree of nucleotide sequences of 163-bp Orthopoxvirus fusion gene amplicons from the patient and rat (head and paw), Cowpox virus, Vaccinia virus (strain Ankara and WR), Camelpox virus, Monkeypox virus, Variola virus, and Ectromelia virus (Mousepox virus). The nucleotide sequences were aligned by using BioEdit software package (T. Hall, Dept. of Microbiology, Raleigh, NC). Phylogenetic relationships were determined by using the Lasergene software packages (DNASTAR Inc., Madison, WI).

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