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Volume 9, Number 1—January 2003

Research

Shiga Toxin–Producing Escherichia coli Infections Associated with Hemolytic Uremic Syndrome, Italy, 1988–2000

Alberto E. Tozzi*Comments to Author , Alfredo Caprioli*, Fabio Minelli*, Alessandra Gianviti†, Laura De Petris†, Alberto Edefonti‡, Giovanni Montini§, Alfonso Ferretti¶, Tommaso De Palo#, Maurizio Gaido**, Gianfranco Rizzoni‡, and the Hemolytic Uremic Syndrome Study Group
Author affiliations: *Istituto Superiore di Sanità, Rome, Italy; †Ospedale Pediatrico Bambino Gesù, Rome, Italy; ‡Pediatric Clinic “De Marchi,” Milan, Italy; §University of Padua, Padua, Italy; ¶Santobono Hospital, Naples, Italy; #Giovanni XXIII Hospital, Bari, Italy; **Regina Margherita Hospital, Turin, Italy.

Main Article

Table

Evidence of STEC infection in 249 Italian children with HUS, shown by presence of prodromal diarrheaa

Evidence of STEC infection Patients with symptoms
no. positive/no. examined (%)
Bloody diarrhea Nonbloody diarrhea No diarrhea No information Total
STEC isolation
9/88 (10.2)
4/63 (6.3)
4/39 (10.2)
1/38 (2.6)
18/228 (7.9)
Free fecal Stx
23/86 (26.7)
21/63 (33.3)
10/38 (26.3)
9/38 (23.7)
63/225 (28.0)
Antibodies to LPS
61/88 (69.3)
39/63 (61.9)
14/41 (34.1)
30/43 (69.8)
144/235 (61.3)
Any 73/92 (79.3) 50/67 (74.6) 22/42 (52.4) 37/48 (77.1) 182/249 (73.1)

aSTEC, Shiga toxin–producing Escherichia coli; HUS, hemolytic uremic syndrome; Stx, Shiga toxin; LPS, lipopolysaccharide.

Main Article

1Members of the Hemolytic Uremic Syndrome Study Group are: A. Bettinelli, G. Capasso, A. Caringella, R. Coppo, G. Lama, S. Li Volti, S. Maffei, S. Maringhini, N. Miglietti, C. Pecoraro, I. Pela, M. Pennesi, R. Penza, L. Peratoner, F. Perfumo, I. Ratsche, E. Salvaggio, C. Setzu, and G. Zacchello.

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