Emerging Infectious Disease ISSN: 1080-6059

Wild-type Measles Virus in Brain Tissue of Children with Subacute Sclerosing Panencephalitis, Argentina

Paola Roxana Barrero*, Jorge Grippo*, Mariana Viegas*, and Alicia Susana Mistchenko*

Author affiliations: *Hospital de Niños Dr. Ricardo Gutiérrez, Buenos Aires, Argentina

Figure 1

Replacement changes found in N and H genes from subacute sclerosing panencephalitis patients. Comparisons were made with D6 genotype reference strain (New Jersey, USA/94/1). Sample Buenos Aires.ARG/21.98 was taken as a consensus sequence for the 1998 Argentine outbreak (ARG21.98). Numbers indicate the position in A-nucleoprotein and B- hemagglutinin protein, respectively. Dots designate the same residue as genotype D6. Nonsilent changes are represented by single letter amino acid code. Antigenic

Figure 1. Replacement changes found in N and H genes from subacute sclerosing panencephalitis patients. Comparisons were made with D6 genotype reference strain (New Jersey, USA/94/1). Sample Buenos Aires.ARG/21.98 was taken as a consensus sequence for the 1998 Argentine outbreak (ARG21.98). Numbers indicate the position in A-nucleoprotein and B- hemagglutinin protein, respectively. Dots designate the same residue as genotype D6. Nonsilent changes are represented by single letter amino acid code. Antigenic sites are underlined.

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