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Volume 9, Number 10—October 2003

Dispatch

Wild-type Measles Virus in Brain Tissue of Children with Subacute Sclerosing Panencephalitis, Argentina

Paola Roxana Barrero*, Jorge Grippo*, Mariana Viegas*, and Alicia Susana Mistchenko*Comments to Author 
Author affiliations: *Hospital de Niños Dr. Ricardo Gutiérrez, Buenos Aires, Argentina

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Table

Clinical, epidemiologic, and laboratory findings for eight pediatric subacute sclerosing panencephalitis (SSPE) patientsa

Patient SSPE1 SSPE2 SSPE3 SSPE4 SSPE5 SSPE6 SSPE7 SSPE8
Date of birth Jan-98 Feb-98 Jul-98 Mar-98 Nov-97 Nov-97 Sep-96 Nov-97
Date of measles disease Sep-98 Sep-98 May-99 Sep-98 Sep-98 N/A Jul-97 Jul-98
Date of SSPE onset May-01 Dec-01 Feb-02 Jun-02 Aug-02 Sep-02 Jan-03 Feb-03
Geographic location GBA GBA NW GBA GBA GBA NE GBA
CSF antibody titers 1:1600 1:1600 1:3200 1:3200 1:400 1:400 1:1600 1:400
Serum antibody titers >1:3200 >1:3200 1:12800 >1:3200 >1:3200 1:12800 N/A 1:400
Initial diagnosis Progressive myoclonic epilepsy Acute disseminated encephalo-myelitis Progressive myoclonic epilepsy Neuronal ceroid lipofucsinosis Lennox Gastaut syndrome Progressive myoclonic atonic epilepsy Chorioretinitis Ataxia

aMolecular studies were done for SSPE patients highlighted in bold type. N/A, not available; GBA, greater Buenos Aires metropolitan area; NW, northwestern region from Argentina; NE, northeastern region from Argentina; CSF, cerebrospinal fluid.

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