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Volume 9, Number 12—December 2003

Research

Human Monocytotropic Ehrlichiosis, Missouri

Juan P. Olano*Comments to Author , Edwin Masters†, Wayne Hogrefe‡, and David H. Walker*
Author affiliations: *University of Texas Medical Branch, Galveston, Texas, USA; †Premier Family Physicians, Cape Girardeau, Missouri, USA; ‡Focus Technologies, Cypress, California, USA

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Table 3

Comparison of selected clinical features and laboratory data between patients with human monocytotropic ehrlichiosis (HME) (case-patient group) and noncase group (control group). Cape Girardeau, Missouri, 1997–1999

Clinical feature HME case-patient group
N (%) Control group
N (%) p value
Fever
29(100)
20(100)
NA
Headache
21(72)
14(70)
0.89a
Dizziness
6(21)
2(7)
0.44b
Myalgia/arthralgia
20(69)
10(50)
0.29a
Chills
13(45)
7(35)
0.69a
Weakness
11(38)
3(15)
0.15a
Nausea
11(38)
3(15)
0.13a
Vomiting
2(7)
2(10)
1.00b
Diarrhea
3(10)
2(10)
1.00b
Abdominal pain
2(7)
1(5)
1.00b
Cough
7(24)
0(0)
0.03b
Sore throat
6(21)
0(0)
0.07b
Rash
6(21)
0(0)
0.07b
Stiff neck
6(21)
0(0)
0.07b
Confusion
2(7)
0(0)
0.50b
Laboratory data
Mean ± SD/median
Mean ± SD/median
p value
Age
48.6 ± 17.5
35.7 ± 19.9
0.02c
Leukocytes x 109 cells/L
4.67
6.25
0.04d
Neutrophils x 109 cells/L
2645
3810
0.03d
Lymphocytes x 109 cells/L
1677
1897
0.36d
Platelets x 109 cells/L
172± 101.8
250.8 ± 137.5
0.06c
Aspartate aminotransferase (U/L) 63 32 0.84d

aCalculated by using Fisher exact test.
bCalculated by using chi-square test.
cCalculated by using t-test.
dCalculated by using Mann-Whitney rank sum test.

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