Figure 2. Axial MRI (magnetic resonance imaging) from patient 2 obtained when first seen in Peru (April 21, 2001), before surgical biopsy in the United States (September 21, 2001), and 7 months after start of treatment (June 7, 2002). The top images are postgadolinium-enhanced, T1-weighted images, which demonstrate resolution of one of the irregular areas of enhancement over time. The bottom images are T2-weighted images (image from April 21 is from a fluid attenuated inversion recovery [FLAIR] sequence), which demonstrate the extensive brain edema associated with these lesions. The right bottom image shows resolution of the brain edema but persistent brain atrophy.