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Volume 9, Number 5—May 2003

Research

Estimating the Incidence of Typhoid Fever and Other Febrile Illnesses in Developing Countries

John A. Crump*Comments to Author , Fouad G. Youssef†, Stephen P. Luby*, Momtaz O. Wasfy†, Josefa M. Rangel*, Maha Taalat†, Said A. Oun‡, and Frank J. Mahoney*†
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †U.S. Naval Medical Research Unit No. 3, Cairo, Egypt; ‡Ministry of Health and Population, Cairo, Egypt

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Table

Incidence estimates for typhoid fever and brucellosis, Bilbeis District, Egypt, 2001

Disease No. of cases captured by surveillance site type
Crude (adjusteda)
Test sensitivity multiplier Seasonality multiplier Total cases Incidence
(/100,000)
Fever hospital) Fever specialist Primary provider Total
Typhoid fever
6.0 (6.0)
13.0 (13.0)
0.0
19.0 (19.0)
2.0
2.2
83.6
12.6
Brucellosis 15.0 (15.0) 12.0 (12.0) 4.0 (27.2) 31.0 (54.2) 1.0 2.2 119.2 18.0

aAdjusted for health provider sampling scheme. No multiplier is applied for cases identified at the fever hospital and among fever specialists. A multiplier of 6.8 is applied for cases identified among primary providers.

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