Figure 3. Map of the spread of dengue virus 3 (DENV-3), subtype III through Latin America and the Caribbean. The introduction of DENV-3, subtype III was first reported in November 1994 in Nicaragua and Panama. This virus strain has been isolated, identified, and reported in at least 16 other countries in the region. *Represents countries with dengue hemorrhagic fever (DHF) caused by DENV-3. These countries are Nicaragua in 1994 and 1998, Brazil and Venezuela in 2001 (Pan American Health Organization, unpub. data).