Volume 9, Number 7—July 2003
Research
Emergence and Global Spread of a Dengue Serotype 3, Subtype III Virus
William B. Messer*, Duane J. Gubler†, Eva Harris‡, Kamalanayani Sivananthan§, and Aravinda M. de Silva*
Table 2
Amino acid substitutions conserved within each dengue virus 3 subtype for the isolates used to create the phylogenetic tree in Figure 1a
| Subtype | Name | Position |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| 31 | 55 | 57 | 128 | 135 | 148 | 188 | 234 | ||
| Outgroup |
56Philipp |
I |
H |
T |
L |
I |
L |
D |
I |
| I |
73Indones |
– |
L |
– |
F |
– |
– |
– |
V |
| I |
74Malaysi |
– |
L |
– |
F |
– |
– |
– |
V |
| I |
78Indones |
– |
L |
– |
F |
– |
– |
– |
V |
| I |
81Malaysi |
– |
L |
– |
F |
– |
– |
– |
V |
| I |
83Philipp |
– |
L |
– |
F |
– |
– |
– |
V |
| I |
85Indones |
– |
L |
– |
F |
– |
– |
– |
V |
| I |
89Tahiti |
– |
L |
– |
F |
– |
– |
– |
V |
| I |
92Fiji |
– |
L |
– |
F |
– |
– |
– |
V |
| II |
62Thailan |
– |
– |
A |
– |
– |
W |
– |
– |
| II |
73Thailan |
– |
– |
A |
– |
– |
– |
– |
– |
| II |
86Thailan |
– |
L |
A |
– |
– |
– |
– |
– |
| II |
87Thailan |
– |
L |
A |
– |
– |
– |
– |
– |
| III |
85Mozamb1 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
85Mozamb2 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
85Mozamb3 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
84IndiaA |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
91Kenya |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
93Somolio |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
81SriLanA |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
83SriLan1 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
83SriLan2 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
83SriLan3 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
83SriLan4 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
84SriLan1 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
85SriLanA |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
85SriLan |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
89SriLan2 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
89SriLanA |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
89SriLan1 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
89SriLan3 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
90SriLan1 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
91SriLanA |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
93SriLan1 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
94SriLan1 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
97SriLan1 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
98SriLan1 |
– |
– |
– |
– |
– |
– |
– |
– |
| III |
86Samoa |
– |
– |
– |
– |
– |
– |
– |
– |
| IV |
63PuertoR |
T |
– |
– |
F |
L |
M |
E |
– |
| IV |
65Tahiti |
T |
– |
– |
F |
L |
M |
E |
– |
| IV | 77PuertoR | T | – | – | F | L | M | E | – |
aReference strain 56Philipp is the highly passaged laboratory strain H87. Positions are numbered sequentially from the first position in the pre-M/M protein.
