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Volume 9, Number 7—July 2003

Research

Emergence and Global Spread of a Dengue Serotype 3, Subtype III Virus

William B. Messer*, Duane J. Gubler†, Eva Harris‡, Kamalanayani Sivananthan§, and Aravinda M. de Silva*Comments to Author 
Author affiliations: *University of North Carolina, Chapel Hill, North Carolina, USA; †Centers for Disease Control and Prevention, Fort Collins, Colorado, USA; ‡University of California, Berkeley, California, USA; §Medical Research Institute, Colombo, Sri Lanka.

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Table 3

Nucleotide substitutions conserved within dengue virus 3, subtype III groupsa

338 429 503 566 653 686 695 707 728 734 749 791 821 866 896 902 978 1010 1019 1056
Reference H87 A A C G G T T G C C C A T C T T C C T C
Group A 83SriLan1 - G T A - - C - - T T - - T C C T T - -
Group A 83SriLan2 - G T A - - C - - T T - - T C C T T - -
Group A 83SriLan3 - G T A - - C - - - T - - T - C - T - -
Group A 83SriLan4 - G T A - - C - - T T - - T C C T T - -
Group A 84SriLan1 - G - - - - - - - - T - - - C - - - - -
Group A 85SriLan1 - G T A - - C - - T T - - T C C T T - -
Group A 89SriLan2 - G T A - - C - - T T - - T C C T T - -
unclassified 84India G G - - A - - - - - T - - - - - - - G -
unclassified 93SriLan1 G G - - A - - - - - - - - - - - - - G -
East Africa 85Mozamb1 G - - - A - - - - - - - - - - - - - G -
East Africa 85Mozamb2 G - - - A - - - - - - - - - - - - - G -
East Africa 85Mozamb3 G - - - A - - - - - - - - - - - - - G -
East Africa 91Kenya G - - - A - - - - - - - - - - - - - G -
East Africa 93Somalia G - - - A - - - - - - - - - - - - - G
Group B 89SriLan1 G G - - A - - A T - - - C - - - - - G -
Group B 89SriLan3 - G - - A - - A T - - - C - - - - - G -
Group B 90SriLan1 G G - - A - - A T - - - C - - C - - G -
Group B 94SriLan1 - G - - A - - A T - - - C - - - - - G -
Group B 97SriLan1 G G - - A - - A T T - - C - C - - - G -
Group B 98SriLan1 G G - - A - - A T - - - C - C - - - G -
L. America 94Nicara1 G G - - A C - - - - - G C - - - - - G T
L. America 94Panama1 G G - - A C - - - - - G C - - - - - G T
L. America 94Panama2 G G - - A C - - - - - G C - - - - - G T
L. America 94Panama3 G G - - A C - - - - - G C - - - - - G T
L. America CostaRica1 G G - - A C - - - - - G C - - - - - G T
L. America CostaRica2 G G - - A C - - - - - G C - - - - - G T
L. America CostaRica3 G G - - A C - - - - - G C - - - - - G T
L. America CostaRica4 G G - - A C - - - - - G C - - - - - G T
L. America 96Mexico1 G G - - A C C - - - - G C - - - - - G T
L. America 96Mexico2 G G - - A C - - - - - G C - - - - - G T
L. America 96Mexico3 G G - - A C - - - - - G C - - - - - G T
L. America 96Mexico4 G G - - A C - - - - - G C - - - - - G T
L. America 97Guatem1 G G - - A C - - - - - G C - - - - - G T
L. America 98Nicara1 G G - - A C - - - - - G C - - - - - G T
L. America 98Nicara2 G G - - A C - - - - - G C - - - - - G T
L. America 98Nicara3 G G - - A C - - - - - G C - - - - - G T
L. America 98ElSalv1 G G - - A C - - - - - G C - - - - - G T
L. America 01Venezue1 G G - - A C - - - - - G C - - - - - G T
L. America 01VEN03 G G - - A C - - - - - G C - - - - - G T
L. America 98PuertoR1 G G - - A C - - - - - G C - - - - - G T
L. America 00PuertoR1 G G - - A C - - - - - G C - - - - - G T

aReference strain is the highly passaged laboratory strain H87. Positions are numbered sequentially from the first nucleotide position at the 5¢ end of the genome.

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